Rosette-forming with sheep's erythrocytes (EAC-RF) and monoclonal antibodies (MCA) were used for account of cell populations and subpopulations in patients with ulcerative colitis and Crohn's disease. It was established that MCA technique does increase accuracy of quantitative determination of immunocompetent cells in such patients but on the whole EAC-RF which is at present more accessible method can be considered quite acceptable for estimation of immune reactivity in nonspecific inflammatory diseases of the colon.

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