Endoscopic laser therapy for small villous adenomas of the duodenum.

Endoscopy

Gastroenterology Unit, St.-Luc University Hospital, Brussels, Belgium.

Published: March 1994

AI Article Synopsis

  • Six patients with nonampullary duodenal adenomas were treated with laser photocoagulation, with all tumors being destroyed in one to five sessions.
  • After a median follow-up of 59 months, no serious side effects were reported, and all patients remained in remission, although one patient died from unrelated cancer.
  • Laser therapy is presented as a viable alternative to surgery for these tumors, particularly for high-risk patients, but ongoing endoscopic monitoring is crucial for identifying recurrences.

Article Abstract

Six patients with seven small, nonampullary duodenal villous or tubulovillous adenomas, two of which showed mild dysplasia, were treated by laser photocoagulation. The mean size of the tumors was 19 +/- 16 mm. Both argon and Nd-YAG lasers were used. All tumors were destroyed in one to five sessions. Recurrences of the lesion in two cases were successfully retreated, and both patients remained free of recurrence after 33 and 48 months, respectively. After a median follow-up of 59 months, all patients remained in remission, and five of them are still alive. One died after six months from a bronchogenic carcinoma. After a total of 18 laser sessions, no serious side-effects were observed, two patients exhibiting a transient melena possibly related to the procedure. We conclude that laser therapy is a good alternative to surgery for nonampullary duodenal villous tumors, especially in high-risk patients. Endoscopic follow-up is mandatory to detect and treat recurrence.

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Source
http://dx.doi.org/10.1055/s-2007-1008973DOI Listing

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