We have found that adenine enhanced the purinoceptor-operated cytoplasmic Ca2+ oscillation in rat megakaryocytes at submillimolar concentrations. Guanine and other nucleic acid bases had no effect on this system. Adenine enhanced the reaction intensity but had no effect on the threshold concentration of ATP to evoke the oscillation.
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| http://dx.doi.org/10.1111/j.1476-5381.1994.tb13076.x | DOI Listing |
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