AI Article Synopsis
- The study examined the prevalence of Helicobacter pylori infection in 20 neonates and young infants from lower socioeconomic backgrounds undergoing ERCP for neonatal cholestasis diagnosis.
- One asymptomatic infant was found to have H. pylori, but a follow-up showed the infection was likely transient with normal histology 14 months later.
- Despite 95% of mothers testing positive for H. pylori and all showing gastritis, neonates and young infants largely remained unaffected by the infection.
Article Abstract
This study was carried out to determine the prevalence of Helicobacter pylori infection in 20 neonates and young infants from lower socioeconomic background undergoing endoscopic retrograde cholangiopancreatography (ERCP) examination for diagnosis of neonatal cholestasis. One young asymptomatic infant (5%) who was breast-feeding with complementary formula had H. pylori infection. Endoscopy showed a normal appearing mucosa and histology demonstrated mild superficial acute gastritis. A follow-up gastroscopy performed 14 months after the initial study showed normal histology without evidence of H. pylori, suggesting that the infection was transient. Nineteen (95%) of the 20 mothers had H. pylori infection, including the mother with the infant positive for H. pylori. All mothers had gastritis on biopsy specimens. Despite the high prevalence of H. pylori in the mothers, infection in neonates and young infants was uncommon.
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| http://dx.doi.org/10.1097/00005176-199405000-00010 | DOI Listing |
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