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United States Pharmacopeia comprehensive safety review of Styphnolobium japonicum flower and flower bud.
Phytother Res
May 2022
Department of Drug Discovery and Development, Harrison School of Pharmacy, Auburn University, Auburn, Alabama, USA.
The dried flower and flower bud of Styphnolobium japonicum (L.) Schott (Japanese Sophora flower and Japanese Sophora flower bud, respectively) have long been used as herbal medicines in Asia. Today, they are marketed as dietary supplements in the United States for their anti-oxidative properties and as a source of flavonoids, including rutin and quercetin.
View Article and Find Full Text PDFArticle Synopsis
- NMR spectroscopy is being used to precisely measure organic molecules, with Hydrogen nucleus quantification (H qNMR) emerging as the primary method for assessing chemical purity.
- A collaborative study involving 13 labs was conducted to validate the H qNMR method, measuring the purity of three samples certified by conventional methods.
- Results showed that H qNMR measurements matched reference values closely, demonstrating its reliability and accuracy comparable to traditional measurement techniques.
Survey to Identify Substandard and Falsified Tablets in Several Asian Countries with Pharmacopeial Quality Control Tests and Principal Component Analysis of Handheld Raman Spectroscopy.
Am J Trop Med Hyg
June 2018
Drug Management and Policy, Faculty of Pharmacy, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan.
The World Health Organization has warned that substandard and falsified medical products (SFs) can harm patients and fail to treat the diseases for which they were intended, and they affect every region of the world, leading to loss of confidence in medicines, health-care providers, and health systems. Therefore, development of analytical procedures to detect SFs is extremely important. In this study, we investigated the quality of pharmaceutical tablets containing the antihypertensive candesartan cilexetil, collected in China, Indonesia, Japan, and Myanmar, using the Japanese pharmacopeial analytical procedures for quality control, together with principal component analysis (PCA) of Raman spectrum obtained with handheld Raman spectrometer.
View Article and Find Full Text PDF[Safe Handling of Cancer Chemotherapy Drugs in Pharmacy(Preparations, Transport and Safe Deposit)].
Gan To Kagaku Ryoho
July 2017
Dept. of Pharmacy, National Cancer Center Hospital East.
Recently, 1 out of 2 people are diagnosed as cancer, the number of patients who are given chemotherapy increases year by year. As a result, amount of anticancer drugs used also increases. Anticancer drug preparation work is one of pharmacist work.
View Article and Find Full Text PDFDevelopment and application of a database of food ingredient fraud and economically motivated adulteration from 1980 to 2010.
J Food Sci
April 2012
US Pharmacopeial Convention, Rockville, MD 20852, USA.
Unlabelled: Food ingredient fraud and economically motivated adulteration are emerging risks, but a comprehensive compilation of information about known problematic ingredients and detection methods does not currently exist. The objectives of this research were to collect such information from publicly available articles in scholarly journals and general media, organize into a database, and review and analyze the data to identify trends. The results summarized are a database that will be published in the US Pharmacopeial Convention's Food Chemicals Codex, 8th edition, and includes 1305 records, including 1000 records with analytical methods collected from 677 references.
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