In four controlled observations on the organized groups of students and industrial workers during the epidemics of influenza A in 1988-1989 Arbidol, a new chemopreparation, was found to be well tolerated and to produce a pronounced prophylactic effect when administered in a dose of 0.2 g (2 tablets of 0.1 g) daily for 10-18 days. After the 18-day prophylactic course of Arbidol the induction of serum interferon was found.
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Org Biomol Chem
January 2025
Jiangxi Provincial Key Laboratory of Functional Crystalline Materials Chemistry, Jiangxi University of Science and Technology, Ganzhou 341000, Jiangxi Province, P.R. China.
The multi-component ring-opening reactions of cyclic ethers offer an efficient strategy for the rapid introduction of multiple functional groups and the construction of complex molecular architectures. Despite the minimal ring strain in five- and six-membered rings presenting a significant challenge for ring-opening, advancements have been made. Traditional acid-catalyzed pathways have been complemented by a novel approach involving carbene-induced oxonium intermediate formation, which has emerged in recent years and expanded the selectivity of ring-opening reactions.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
Haiping Fang, School of Physics, East China University of Science and Technology, Shanghai, 20023, China.
The human visual nervous system excels at recognizing and processing external stimuli, essential for various physiological functions. Biomimetic visual systems leverage biological synapse properties to improve memory encoding and perception. Optoelectronic devices mimicking these synapses can enhance wearable electronics, with layered heterojunction materials being ideal materials for optoelectronic synapses due to their tunable properties and biocompatibility.
View Article and Find Full Text PDFAdv Sci (Weinh)
January 2025
SKKU Advanced Institute of Nanotechnology (SAINT) and Department of Nano Science and Technology, Sungkyunkwan University, Suwon, 16419, Republic of Korea.
A novel additive method to boost the Seebeck coefficient of doped conjugated polymers without a significant loss in electrical conductivity is demonstrated. Perovskite (CsPbBr) quantum dots (QDs) passivated by ligands with long alkyl chains are mixed with a conjugated polymer in a solution phase to form polymer-QD blend films. Solution sequential doping of the blend film with AuCl solution not only doped the conjugated polymer but also decomposed the QDs, resulting in a doped conjugated polymer film embedded with separated ions dissociated from the QDs.
View Article and Find Full Text PDFChemistry
January 2025
Key Laboratory of Science and Technology of Eco-Textiles, Ministry of Education, College of Chemistry and Chemical Engineering, Donghua University, Shanghai, 201620, P. R. China.
We have developed an efficient synthesis of fluoroalkenes via tandem electrochemical dehalogenation-elimination protocol. The key step is the generation of carbon anion by electrochemical reductive dehalogenation of alkyl halides. Various gem-difluoroalkenes and monofluoroalkenes were prepared in moderate to good yields from α-difluoromethylated/α-trifluoromethylated benzyl halides.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Institute of Advanced Materials (INAM), Universitat Jaume I, Av. Vicent Sos Baynat, s/n, 12071 Castellón de la Plana, Spain.
High defect concentrations at the interfaces are the basis of charge extraction losses and instability in perovskite solar cells. Surface engineering with organic cations is a common practice to solve this issue. However, the full implications of the counteranions of these cations for device functioning are often neglected.
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