[The structural-functional changes in the hepatobiliary system of patients with colorectal cancer].

On the grounds of clinical and experimental data on hepatobiliary system obtained by hepatobiliscintigraphy (HBSG) and morphological study of hepatic parenchyma deterioration of hepatocytes and suppression of concentrating abilities of gallbladder were found in 68 patients with colorectal cancer and no clinical and laboratory manifestation. Any antitumor treatment, especially combined with chemotherapy, aggravates the disorders. Surgical intervention provokes transient ciliary dyskinesia. Unspecific reactive hepatitis associated with intrahepatic cholestasis and aggravated by antitumor therapy should be considered as a morphological ground for the functional changes. HBSG is recommended to be performed from time to time during post-operative rehabilitation of patients who underwent radical surgery for colorectal cancer. Correction of revealed disorders should be carried out in gastroenterological departments.