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Effect of a glutamine-enriched diet on small bowel allograft during immunosuppressive therapy.
Nutrition
September 1997
Department of Surgery II, School of Medicine, Kanazawa University, Japan.
The effect of an orally administered glutamine-enriched elemental diet was examined following orthotopic small bowel allotransplantation using Brown Norway rats as donors and Lewis rats as recipients. The recipients was treated with FK 506 and randomized to receive glutamine-free elemental enteral diet solution (glutamine-free group), glutamine-enriched elemental diet solution containing 7500 mg of glutamine per 100 g diet (glutamine-enriched group) or standard chow (chow group) ad libitum for 7 d. There were no histological changes due to resection.
View Article and Find Full Text PDFProtective effects of glutamine enriched diets on acute actinic enteritis.
Nutr Hosp
December 1996
Surgical Technique Laboratory (Surgical Department), University of Sao Paulo Medical School, Brazil.
Radiotherapy plays an important role in cancer treatment, although it may cause collateral effects and sever complications due to cellular damage of peritumoral tissues. Recently different nutritional resources have been indicated to achieve intestinal protection during cancer irradiation. The aim of this study was to set the role of glutamine in acute actinic enteritis prevention.
View Article and Find Full Text PDFEfficacy of glutamine-enriched enteral nutrition in an experimental model of mucosal ulcerative colitis.
Br J Surg
June 1995
First Department of Surgery, Jikei University School of Medicine, Tokyo, Japan.
Intact intestinal epithelium and associated lymphatic tissue act as body defences against luminal toxins. This barrier may become threatened or compromised in inflammatory bowel disease, leading to an increase in mucosal permeability and subsequent translocation of endotoxins. The effect of oral glutamine on gut mucosal ornithine decarboxylase activity and on endotoxin levels in portal vein blood was studied in a guinea-pig model of carrageenan-induced colitis.
View Article and Find Full Text PDFEffect of a glutamine-enriched elemental diet on regeneration of the small bowel mucosa following isotransplantation of small intestine.
Transplant Proc
August 1994
Department of Surgery II, School of Medicine, Kanazawa University, Japan.
Prevention of radiogenic side effects using glutamine-enriched elemental diets.
Recent Results Cancer Res
August 1991
College of Medicine, University of Florida, Gainesville 32610.
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