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Non-oliguric acute renal failure secondary to a potentially lethal dose of caffeine with acute intoxication: a case report.
BMC Nephrol
December 2024
Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, 247-8533, Kanagawa, Japan.
Background: Recently, the incidence of caffeine intoxication has been on an upward trend, with severe outcomes. However, acute kidney injury (AKI) resulting from renal pathologies secondary to caffeine intoxication is rare, and the pathophysiological mechanisms underlying AKI are unclear.
Case Presentation: A female patient in her 20s ingested an over-the-counter drug containing caffeine.
Bromadiolone may cause severe acute kidney injury through severe disorder of coagulation: a case report.
BMC Nephrol
September 2024
Department of Nephrology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University, Nanjing, 210029, China.
Article Synopsis
- Bromadiolone is a long-acting anticoagulant rodenticide that can lead to serious coagulation issues, but cases of acute kidney injury (AKI) due to its poisoning haven't been reported until now.
- A 27-year-old woman developed severe coagulopathy and AKI after bromadiolone exposure, indicating a vitamin K deficiency; her kidney function worsened but later fully recovered with treatment.
- This case highlights that bromadiolone can cause AKI through severe coagulation dysfunction, which can be treated effectively with high doses of vitamin K and plasma transfusion.
Bilateral primary renal diffuse large B-cell lymphoma: a rare presentation of paediatric renal disease mimicking juvenile nephronophthisis.
BMJ Case Rep
July 2020
Department of Paediatrics, NHS Greater Glasgow and Clyde, Glasgow, UK.
A 12-year-old boy presented with a prolonged history of headache, fatigue and hypertension. Initial investigations were consistent with presumed non-oliguric end-stage renal disease, leading to a provisional diagnosis of juvenile nephronophthisis. Subsequent imaging demonstrated bilaterally enlarged kidneys without cystic change.
View Article and Find Full Text PDFThe clinical relevance of oliguria in the critically ill patient: analysis of a large observational database.
Crit Care
April 2020
Departament of Anaesthesiology and Intensive Care, Uniklinikum Jena, Jena, Germany.
Background: Urine output is widely used as one of the criteria for the diagnosis and staging of acute renal failure, but few studies have specifically assessed the role of oliguria as a marker of acute renal failure or outcomes in general intensive care unit (ICU) patients. Using a large multinational database, we therefore evaluated the occurrence of oliguria (defined as a urine output < 0.5 ml/kg/h) in acutely ill patients and its association with the need for renal replacement therapy (RRT) and outcome.
View Article and Find Full Text PDFImpact of loop diuretics on critically ill patients with a positive fluid balance.
Anaesthesia
January 2020
Medical Sciences Postgraduate Program, Department of Clinical Medicine, Universidade Federal do Ceará, Fortaleza, Ceara, Brazil.
The impact of the use of loop diuretics to prevent cumulative fluid balance in non-oliguric patients is uncertain. This is a retrospective study to estimate the association of time-averaging loop diuretic exposure in a large population of non-cardiac, critically ill patients with a positive fluid balance (> 5% of body weight). The exposure was loop diuretic and the main outcomes were 28-day mortality, severe acute kidney injury and successful mechanical ventilation weaning.
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