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Multi-Method Analysis of Histopathological Image for Early Diagnosis of Oral Squamous Cell Carcinoma Using Deep Learning and Hybrid Techniques.
Cancers (Basel)
October 2023
Computer Sciences Department, College of Computer and Information Sciences, Princess Nourah Bint Abdulrahman University (PNU), Riyadh 11671, Saudi Arabia.
Oral cancer is a fatal disease and ranks seventh among the most common cancers throughout the whole globe. Oral cancer is a type of cancer that usually affects the head and neck. The current gold standard for diagnosis is histopathological investigation, however, the conventional approach is time-consuming and requires professional interpretation.
View Article and Find Full Text PDFA Multilevel Bayesian Approach to Improve Effect Size Estimation in Regression Modeling of Metabolomics Data Utilizing Imputation with Uncertainty.
Metabolites
August 2020
Michigan Center for Integrative Research in Critical Care (MCIRCC), University of Michigan, Ann Arbor, MI 48109, USA.
To ensure scientific reproducibility of metabolomics data, alternative statistical methods are needed. A paradigm shift away from the -value toward an embracement of uncertainty and interval estimation of a metabolite's true effect size may lead to improved study design and greater reproducibility. Multilevel Bayesian models are one approach that offer the added opportunity of incorporating imputed value uncertainty when missing data are present.
View Article and Find Full Text PDFAutomated in-process characterization and selection of cell-clones for quality and efficient cell manufacturing.
Cytotechnology
October 2020
Department of Biomedical Engineering, Lerner Research Institute, Cleveland Clinic, Cleveland, OH, 44195, USA.
Delivery of safe, effective and reliable cellular therapies, whether based on mesenchymal stromal cells (MSCs) or induced pluripotent stem cells (iPSCs), demand standardization of cell culture protocols. There is a need to develop automation platform that enables the users to generate culture expanded human cell populations that improves the quality and reduces batch-to-batch variation with respect to biological potential. Cell X™ robot was designed to address these current challenges in the cell fabrication industry.
View Article and Find Full Text PDFAnatomic distribution and mortality of arterial injury in the wars in Afghanistan and Iraq with comparison to a civilian benchmark.
J Vasc Surg
September 2012
United States Army Institute for Surgical Research, Fort Sam Houston San Antonio, San Antonio, Tex 78234, USA.
Objective: The purpose of this study was to examine the anatomic distribution and associated mortality of combat-related vascular injuries comparing them to a contemporary civilian standard.
Design: The Joint Trauma Theater Registry (JTTR) was queried to identify patients with major compressible arterial injury (CAI) and noncompressible arterial injury (NCAI) sites, and their outcomes, among casualties in Iraq and Afghanistan from 2003 to 2006. The National Trauma Data Bank (NTDB) was then queried over the same time frame to identify civilian trauma patients with similar arterial injuries.
Standards for immunization practice for vaccines in children and adults.
Infect Dis Clin North Am
March 2001
Department of Pediatrics, Brown University School of Medicine, and Division of Pediatric Infectious Diseases, Rhode Island Hospital, Providence, Rhode Island, USA.
Administration of vaccines is a continuing challenge. In childhood immunizations, many of the goals for national coverage rates by 2000 were achieved and the goal of annual influenza immunization for adults 65 years of age and older was reached. These successes in childhood immunization rates have led to record low numbers of cases of many vaccine-preventable diseases, such as measles and Haemophilus influenzae, type b invasive disease.
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