'Gelbsilber' (GS) rabbits which had been maintained for an unknown time as a closed colony, were found to respond uniformly well to the pig lactic dehydrogenase isoenzyme of the H4 type (P-LDH-H4), to which most New Zealand white (NZW) rabbits produced no detectable antibody. Two to three per cent of the splenic lymphoid cells of GS rabbits after secondary immunization were found to produce antibody to P-LDH-H4, while no such cells were detected in NZW rabbits. No differences were detected between the electrophoretic mobility of endogenous LDH of GS and NZE rabbits. The immunoglobulins of GS rabbits were heterogeneous with respect to immunoglobulin light and heavy chain allotypes. It was concluded that in GS rabbits the response to LDH-H4 is controlled by and Ir gene and that these animals might be useful in studying the genetic control of the immune response in rabbits.
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[Experimental ultrasonography of the rabbit eye (author's transl)].
Albrecht Von Graefes Arch Klin Exp Ophthalmol
May 1976
In 20 adult rabbits of the Gelbsilber-strain the axial depth of the anterior chamber, the axial thickness of the lens, and 7 different diameters of the vitreous chamber were measured by means of bioechometry for standardization of the to date neglected experimental ultrasonography of animal eyes. For proper interpretation of echograms of the rabbit eye the particular anatomy and topography of the lens must be considered. Penetration of the large and almost spherical lens by the beam can only be avoided if the probe is placed behind the limbus or behind the equator of the globe.
View Article and Find Full Text PDF'Gelbsilber' (GS) rabbits which had been maintained for an unknown time as a closed colony, were found to respond uniformly well to the pig lactic dehydrogenase isoenzyme of the H4 type (P-LDH-H4), to which most New Zealand white (NZW) rabbits produced no detectable antibody. Two to three per cent of the splenic lymphoid cells of GS rabbits after secondary immunization were found to produce antibody to P-LDH-H4, while no such cells were detected in NZW rabbits. No differences were detected between the electrophoretic mobility of endogenous LDH of GS and NZE rabbits.
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