A case of leiomyosarcoma of the spinal leptomeninges is presented, with clinical, radiological, light microscopic and immunohistochemical data. The probable origin of the tumor from a pluripotent mesenchymal cell is discussed.
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http://dx.doi.org/10.1007/BF01324600 | DOI Listing |
J Neurooncol
November 2024
Department of Neurosurgery, Allegheny Health Network Neuroscience Institute, Pittsburgh, PA, USA.
Purpose: Sarcomas metastasizing to the spine are a rare entity. Ideally an En-bloc resection is necessary to achieve durable local control (LC) rates. However, anatomical constraints often limit the degree of tumor resection.
View Article and Find Full Text PDFSurg Neurol Int
April 2024
Department of Neurology, Požega County Hospital, Požega, Požeško-Slavonska, Croatia.
Background: Leiomyosarcoma (LMS) is a rare malignancy that originates from smooth muscle. The most common sites of metastases include the lungs, liver, kidney, and skin. Notably, metastases of LMS to the central nervous system/or spine are extremely rare.
View Article and Find Full Text PDFJ Neurosurg Spine
April 2024
1Departments of Neurosurgery.
Objective: Leiomyosarcoma (LMS) is a rare, aggressive soft-tissue sarcoma that seldom spreads to the bone. The spine can be either the site of LMS osseous metastases or the primary tumor site. The optimal treatment option for spinal LMS is still unclear.
View Article and Find Full Text PDFSpinal Cord Ser Cases
July 2023
Department of Neurological Surgery, Montefiore Medical Center, Bronx, NY, USA.
Introduction: Primary CNS leiomyosarcomas are rare, dural-based intracranial or intravertebral tumors seen in immunocompromised patients and are associated with latent EBV infection. They may mimic a meningioma or schwannoma on imaging but their clinical presentation progresses much more rapidly. Often times, these tumors are hard to distinguish from secondary, metastatic leiomyosarcoma.
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