Rabbit and mice were injected into the blood stream sodium hyaluronate (0.1 mg per 1 g of the body animal) and protein-chondroitin-keratan-sulfate sodium (0.2 mg per 1 g of the body animal) in 0.15 M NaCl solution. It was shown that both proteoglycans in the blood stream the aggregation action on the erythrocytes in the blood stream. The action finished after 24 hours later on the injection of proteoglycans during in which time the circulating the proteoglycans is remove out of the plasma.
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