Methods: A number of ab interno and ab externo sclerostomy procedures have been described in recent years.
Conclusion: At the present time, there is no clear indication that such interventions are superior to the classical fistulizing glaucoma operations, such as trabeculectomy.
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http://dx.doi.org/10.1055/s-2008-1035539 | DOI Listing |
Int J Mol Sci
November 2024
Department of Ophtalmology, General Hospital Zadar, Ul. Bože Peričića 5, 23000 Zadar, Croatia.
Long-term use of topical prostaglandins might initiate chronic conjunctival inflammation, leading to poor outcomes of glaucoma surgery. The aim of this study was to evaluate the immunoexpression pattern of HSP70, CTGF, SNAIL, aSMA, cMYB, and HIFa in the conjunctiva, episclera, and deep sclera in patients with glaucoma undergoing deep sclerectomy in order to establish an association between staining intensities and prostaglandin F2 (PGF2) treatment. Double immunofluorescence (HSP70, CTGF, SNAIL, aSMA, cMYB, and HIFa) was performed on conjunctiva, episclera, and deep sclera samples, which were obtained from 23 patients treated with PGF2 and 8 patients without PGF2 treatment.
View Article and Find Full Text PDFVestn Oftalmol
November 2024
Krasnov Research Institute of Eye Diseases, Moscow, Russia.
Purpose: This study assesses the impact of preoperative administration of Oku-Oku eye drops on the severity of conjunctival hyperemia and the risk of hemorrhagic complications in the early postoperative period following glaucoma surgery.
Material And Methods: The study included a group of 30 patients (30 eyes) with uncontrolled primary open-angle glaucoma who underwent non-penetrating deep sclerectomy. The main group included 15 eyes, in which Oku-Oku drops were administered twice - on the day before surgery (upon hospital admission) and immediately before the operation.
Cureus
October 2024
Ophthalmology, Atrium Health Wake Forest Baptist, Winston-Salem, USA.
Purpose This study evaluates the impact of phacoemulsification on trabeculectomy bleb morphology and intraocular pressure (IOP) control in patients with primary angle closure glaucoma (PACG). The study also evaluates possible alterations in these effects by intra-operative blocking of internal sclerostomy by high-density viscoelastic (visco-cushion). Methods This is a single-center, interventional, prospective study including patients with PACG who underwent phacoemulsification post-trabeculectomy.
View Article and Find Full Text PDFOphthalmol Sci
August 2024
St Paul's Eye Unit, Royal Liverpool University Hospital, Liverpool, UK.
Purpose: To investigate the use of anterior-segment OCT (AS-OCT) to visualize the aqueous outflow pathway and patency of the scleral flap in glaucoma filtration surgery blebs.
Design: Cross-sectional study.
Subjects: Two hundred five filtering blebs of 112 patients with glaucoma who had undergone trabeculectomy (Trab, n = 97) or deep sclerectomy (DS, n = 108) surgery with/without mitomycin-C (MMC).
Curr Eye Res
December 2024
Faculty of Medicine, Department of Ophthalmology, Istanbul Medeniyet University, Istanbul, Turkey.
Purpose: This study presents a novel sutureless closure approach for sclerotomies following pars plana vitrectomy (PPV) and assesses its efficacy and safety.
Methods: A total of 142 eyes were included in the study. PPV procedures were performed using 23-gauge (23 G) or 25-gauge (25 G) systems.
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