A case of intramammary solitary schwannoma (SS) (benign neurilemoma) diagnosed by fine-needle aspiration biopsy (FNAB) and supported by immunocytochemical study is reported. The tumor arose in the right breast of an 18-yr-old woman and was clinically and radiologically considered a fibroadenoma. The smears obtained by FNAB of the lump showed clusters of spindle-shaped cells and suggested a benign mesenchymal neoplasm. The presence of some structures reminiscent of Verocay bodies and the immunocytochemical reactivity for S-100 protein antiserum demonstrated the schwannian nature of the tumor and suggested the diagnosis of SS. The final histologic examination confirmed the cytologic diagnosis.
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Article Synopsis
- Neuropathologic entities, though rare, can affect the sinonasal tract through different mechanisms including embryological defects and ectopic tissue remnants.
- These entities may also arise from benign tumors that extend from the brain or nearby structures, such as pituitary adenomas and meningiomas.
- Additionally, high-grade intracranial tumors like glioblastomas can invade the sinonasal area, making it essential for surgical pathologists to include these in the differential diagnoses of unusual sinonasal lesions.
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