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Clinical review and drug sensitivity test of complex isolates in non-lactating patients with severe mastitis.
Front Microbiol
December 2024
Department of Laboratory Medicine, Guangdong Provincial Hospital of Chinese Medicine, Zhuhai, China.
Background: Previous microbiological investigations have demonstrated a significant correlation between complex (CKC) infection and mastitis. Recent studies have confirmed the existence of the CKC, with () identified as the primary infectious agent. Examining the incidence of CKC in cases of severe non-lactational mastitis, alongside the clinical characteristics of infected patients, as well as evaluating the drug sensitivity testing protocols for CKC, can provide a more robust foundation for the diagnosis and treatment of CKC infections.
View Article and Find Full Text PDFThe association of hypokalemia with meropenem administration: A case report and literature review.
J Res Med Sci
November 2024
Department of Geriatric Medicine, Milton Keynes University Hospital NHS Foundation Trust, Eaglestone, Milton Keynes, Buckinghamshire, UK.
We report the case of a 72-year-old woman who was admitted following a fall and sustained a right neck of femur fracture. Prior to this admission, she was undergoing chemotherapy for lung cancer. Upon this admission, it was noted that she had developed neutropenic sepsis.
View Article and Find Full Text PDFAssessment of the potential and application of BeO nanocage for removal of ciprofloxacin from water employing density functional theory.
Sci Rep
January 2025
Department of Pharmacology and Toxicology, College of Pharmacy, King Saud University, 11451, Riyadh, Saudi Arabia.
The modern world is facing the issue of emerging pollutants for its sustainable development. We report a detailed study on the abatement of ciprofloxacin (CIP) by BeO nanocage. Five different geometries of BeO nanocage with CIP i.
View Article and Find Full Text PDFEffect of tropical climates on the quality of commonly used antibiotics: the protocol for a systematic review and meta-analysis.
BMJ Open
January 2025
Clinical Research Department, KEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Introduction: Medicine quality can be influenced by environmental factors. In low- and middle-income countries (LMICs) with tropical climates, storage facilities of medicines in healthcare settings and homes may be suboptimal. However, knowledge of the effects of temperature and other climatic and environmental factors on the quality of medicines is limited.
View Article and Find Full Text PDFInsight into the effect of ZIF-8 on the interaction between drugs and protein/cell.
Int J Biol Macromol
January 2025
School of Pharmaceutical Sciences, Liaoning University, Shenyang 110036, China. Electronic address:
Understanding the impact of nanomaterials on drug-protein/cell interactions is crucial for comprehending their in vivo biological effects. We investigated the impact of zeolitic imidazolate framework (ZIF)-8 on the interaction between curcumin (Cur) and human serum albumin (HSA) using various spectroscopic techniques and molecular docking. Additionally, we examined its effect on drug-cell interaction using HepG2 cells and Escherichia coli (E.
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