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Mesenchymal Stem Cell-conditioned Medium Attenuated CoCl2-induced Injury of Renal Tubular Epithelial Cells by Inhibiting NCOA1, HIF-1α, and Sox9.
Curr Pharm Des
January 2025
Department of Nephrology, the Second Affiliated Hospital of Shantou University Medical College, Shantou, 515041, China.
Backgrounds: Renal interstitial fibrosis (RIF) constitutes the ultimate pathological alteration in nearly all chronic kidney diseases (CKD). Mesenchymal stem cell conditioned medium (MSC-CM) exhibits an alleviating impact on renal fibrosis; however, the underlying mechanism remains unclear. The objective of this study was to explore whether MSC-CM regulates the expression of α-smooth muscle actin (α-SMA), Transforming growth factor-β1 (TGF-β1), Hypoxia-inducible factor-1α (HIF-1α), Nuclear receptor coactivators (NCOA1), and SRY-related high mobility (Sox9).
View Article and Find Full Text PDFPollen-pistil interaction in Mauritia flexuosa: structural and cytological aspects provide insight into the reproductive success of a dioecious palm with supra-annual flowering in a semiarid environment.
Plant Biol (Stuttg)
January 2025
Laboratório de Ecologia Vegetal, Departamento de Biologia Geral, Universidade Estadual de Montes Claros, Montes Claros, Minas Gerais, Brazil.
The success of pollen-pistil interaction in Mauritia flexuosa (buriti), a palm adapted to the humid ecosystems, 'veredas', within the Cerrado, is influenced by intrinsic and environmental factors. Its supra-annual flowering, dioecy, and adverse climate conditions pose challenges for fertilization, therefore information on floral biology is essential. This study aimed to ascertain stigma receptivity, and elucidate structural, cytochemical, and ultrastructural aspects of the pollen-pistil relationship.
View Article and Find Full Text PDFDevelopmental studies of the sublingual and mandibular salivary glands in Japanese quails (Coturinx coturinx japonica).
BMC Vet Res
November 2024
Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Assiut University, Assiut, Egypt.
Article Synopsis
- The Japanese quail has been significant to humans since the 12th century, known for its high egg production, quality low-fat meat, and ease of management, making it valuable in both industry and research.
- A study focused on the development of the oropharyngeal salivary glands in Japanese quails, examining embryos and chicks at various ages using histological and electron microscopy techniques.
- Key findings included the early formation of sublingual and mandibular glands, which developed into mucous glands after hatching, playing important roles in food processing and moisture retention during feeding.
Innovative Biocompatible Blend Scaffold of Poly(hydroxybutyrate-co-hydroxyvalerate) and Poly(ε-caprolactone) for Bone Tissue Engineering: In Vitro and In Vivo Evaluation.
Polymers (Basel)
October 2024
Centro de Ciências Naturais e Humanas (CCNH), Universidade Federal do ABC (UFABC), São Bernardo do Campo 09606-070, Brazil.
This study evaluated the biocompatibility of dense and porous forms of Poly(hydroxybutyrate-co-hydroxyvalerate) (PHBV), Poly(ε-caprolactone) (PCL), and their 75/25 blend for bone tissue engineering applications. The biomaterials were characterized morphologically using scanning electron microscopy (SEM) and Fourier transform infrared spectroscopy (FTIR), and the thickness and porosity of the scaffolds were determined. Functional assessments of mesenchymal stem cells (MSCs) included the MTT assay, alkaline phosphatase (ALP) production, and morphological and cytochemical analyses.
View Article and Find Full Text PDFMicromorphology and native extractive behaviour of wood powder.
Sci Rep
October 2024
Department of Forest Biomaterials and Technology/Wood Science, Swedish University of Agricultural Sciences, Uppsala, SE-756 51, Sweden.
Article Synopsis
- * This study examines how different milling methods and moisture levels in wood affect the microstructure and distribution of extractives in the wood powders.
- * Results indicate that wood powders from multi-blade shaft milling maintain a smoother and more intact structure, while hammer mill powders show rougher surfaces and more damage, affecting their potential use in future applications.
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