We report on a prospective study of 152 children aged 3 months to 5 years, from a community pediatric clinic, who had signs of pharyngitis, temperature > or = 38 degrees C and were not treated by antibiotics during the preceeding week. Nose and throat cultures were taken from each child. Blood antistreptolysin (ASO) was examined. If the cultures were positive for group A beta hemolytic Streptococcus (GABHS), a second blood sample for ASO was obtained later. True streptococcal infection was defined in a case of a positive culture and an increase in the ASO titer of at least two tubes, while cases of positive cultures without significant changes in ASO titer were defined as carriers. Positive GABHS cultures were found in 23 cases. True group A Streptococcus infection was found only in patients > 2 years old. The carriers of GABHS increased gradually from 3% during the 1st year to 22% by the 5th year. This study demonstrated that in the population evaluated, the incidence of true GABHS infection in children < 2 years of age is low, as was observed in the past.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Acute Rheumatic Fever or Post-streptococcal Reactive Arthritis: Two Different Entities.
Cureus
October 2024
Internal Medicine, Hospital São Teotónio, Viseu, PRT.
Article Synopsis
- A 71-year-old man experienced fever and joint pain after a recent throat infection, showing signs of group A streptococcal (GAS) infection with high antistreptolysin O (ASO) levels.
- The case raised questions about whether he had acute rheumatic fever (ARF) or post-streptococcal reactive arthritis (PSReA), as he displayed symptoms of both conditions.
- The authors highlight the need for careful consideration of ARF in patients with recent streptococcal infections and joint pain to ensure timely treatment and avoid complications.
Anti-SARS-CoV-2 gapmer antisense oligonucleotides targeting the main protease region of viral RNA.
Antiviral Res
October 2024
Research Center for Drug and Vaccine Development, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan; Department of Virology II, National Institute of Infectious Diseases, Tokyo, 162-8640, Japan; Department of Applied Biological Sciences, Tokyo University of Science, Noda, 278-8510, Japan; MIRAI, JST, Tokyo, 102-0076, Japan. Electronic address:
Article Synopsis
- Emerging respiratory viruses like SARS-CoV-2 pose a global risk, prompting the need for new antiviral strategies, particularly through the use of gapmer antisense oligonucleotides (ASOs).
- Researchers synthesized about 300 ASOs targeting different regions of the SARS-CoV-2 RNA and effectively identified ASO#41, which inhibited viral replication and reduced infection-related cell damage.
- ASO#41 demonstrated strong antiviral activity against multiple variants of SARS-CoV-2 in lab models and showed promise in mice, indicating its potential as a targeted treatment approach for respiratory viruses.
Role of H.pylori in Chronic Sore Throat by Using H.pylori Line.
Indian J Otolaryngol Head Neck Surg
June 2024
Clinical Pathology, Students Hospital, Mansoura University, Mansoura, Egypt.
Pharyngitis is an inflammation of the mucous membranes of the oropharynx. Pharyngitis may be caused by an infectious or noninfectious disease. Noninfectious diseases of pharynx include allergies, trauma, cancer, reflux and certain toxins.
View Article and Find Full Text PDFCase report of streptococcal infection as a potential precipitating factor in cutaneous polyarteritis nodosa in pediatric patients.
Clin Case Rep
June 2024
Department of Pediatrics Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences Tehran Iran.
Key Clinical Message: This pediatric case report underscores the importance of maintaining a high clinical suspicion for polyarteritis nodosa (PAN) in patients presenting with atypical features, such as migratory arthritis and subcutaneous nodules. Importantly, it highlights the focus on the potential relationship between streptococcal infection and cutaneous PAN. Early recognition and prompt, aggressive treatment is critical, as PAN can be a life-threatening condition if left unmanaged.
View Article and Find Full Text PDFOcular Tics and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS).
Diseases
April 2024
Department of Medicine, Surgery, and Pharmacy, University of Sassari, 07100 Sassari, Italy.
Little is known about ocular tics in Pediatric Autoimmune Neuropsychiatric Disorders associated with Streptococcal infections (PANDAS). In this retrospective study, we examined the clinical records of children with motor tics referred to the Ophthalmology Unit, Azienda Ospedaliero-Universitaria di Sassari, Italy, in 2010-2019. The presence of ocular tics was investigated.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!