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Background: The pathogenesis of female pelvic floor polypropylene mesh complications is unclear as trials evaluating explanted mesh have not included asymptomatic controls.
Objectives: To compare explanted polypropylene mesh from those with and without mesh complications to determine the pathogenesis of the complications.
Methods: Between August 2019 and July 2020 66 participants attending Wesley and Royal Brisbane and Women's Hospital Urogynecology department with mesh complications and 15 undergoing repeat prolapse and/or continence surgery after prior polypropylene mesh implantation were included.
Multinuclear Silver(I)-Selenium Clusters Formation in Selenopeptides.
Inorg Chem
March 2025
Université de Pau et des Pays de l'Adour, E2S UPPA, CNRS, IPREM, 2 Avenue du Président Pierre Angot, Pau 64053, France.
The reactions of ionic silver (Ag) with arginine vasopressin (AVP), a nonapeptide hormone cyclized by two cysteine residues, and its diselenium analogue was explored by an integrated LC-MS, UV-vis, and DFT approach. The replacement of Cys by SeCys in AVP increased the reactivity of the peptide toward Ag ions under mildly reducing conditions, with the formation of a SeAg cluster provided by Ag(I)-mediated dimerization of diselenide AVP. Specific electronic absorption bands confirmed the formation of the Agpeptide complex, supported by DFT calculations.
View Article and Find Full Text PDFEffects of Female Sex Hormone Therapy on Nasal Mucosa.
Indian J Otolaryngol Head Neck Surg
February 2025
I.M. Sechenov First Moscow State Medical University, Moscow, Russia.
Women worldwide commonly use combined oral contraceptives (COCs) and hormone replacement therapy(HRT). Nevertheless, there is still ambiguity regarding the possible influence of these hormone therapy on the nasal mucosa. A systematic review was performed according to PRISMA guidelines.
View Article and Find Full Text PDFAllergen Immunotherapy in Autoimmune Terrain: A Case Study.
Indian J Otolaryngol Head Neck Surg
January 2025
Department of Endocrinology, Joshi Clinic, Mumbai, India.
Allergen immunotherapy (AIT), or specific immunotherapy (SIT), is an effective treatment for inducing immune tolerance to specific allergens. It is widely used for allergic rhinitis, conjunctivitis, asthma, and Hymenoptera venom allergies, with recent applications to food allergies and atopic dermatitis. Despite its benefits, the use of SIT in patients with autoimmune diseases is controversial due to concerns about its potential to induce or exacerbate autoimmune conditions.
View Article and Find Full Text PDFAssociation of endometrial thickness with lesions in postmenopausal asymptomatic women: risk factors and diagnostic thresholds.
BMC Womens Health
March 2025
Department of Obstetrics and Gynecology, Beijing Shijitan Hospital, Capital Medical University, No. 10 Tieyi Road, Yangfangdian Street, Haidian District, Beijing, China.
Purpose: This study aimed to explore the relationship between endometrial thickness and lesions in asymptomatic postmenopausal women and identify diagnostic thresholds for lesions.
Methods: A total of 279 postmenopausal asymptomatic women aged 40 years or older with endometrial thickness ≥ 4 mm were retrospectively selected in our hospital, from January 2018 to June 2023, there were 33 cases's operations which were failed due to the cervical stenosis, 8cases who used hormone replacement therapy within the past year, 7 cases with hysteromyoma that affect the shape of the uterine cavity line, and 5cases's hysteroscopic tissue acquisition were failed. Finally, A retrospective study was conducted on the endometrial thickness of 226 postmenopausal asymptomatic women measured by transvaginal ultrasound and those with thickening were subjected to hysteroscopy and pathological examination of endometrial biopsy tissues, and were divided into a normal group (80 cases), benign lesion group (143 cases), and malignant lesion group (3 cases) according to the pathology results.
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