Pulsatile gonadotropin releasing hormone (GnRH)--treatment for hypothalamic amenorrhoea causing infertility.

Acta Obstet Gynecol Scand

Specialist Open-care Unit of Obstetrics and Gynecology, Uppsala, Sweden.

Published: July 1994

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Article Abstract

Thirty women with hypothalamic amenorrhoea and infertility were treated with pulsatile GnRH s.c. without monitoring with estradiol and ultrasonography. Ovulation rate per patient was 93%. Ovulation rate per cycle was 90%. Pregnancy rate per ovulatory cycle 30%. Miscarriage rate 18.5%. 23 children were born including one set of twins. No serious side effects were recorded.

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http://dx.doi.org/10.3109/00016349409013436DOI Listing

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