Thirty women with hypothalamic amenorrhoea and infertility were treated with pulsatile GnRH s.c. without monitoring with estradiol and ultrasonography. Ovulation rate per patient was 93%. Ovulation rate per cycle was 90%. Pregnancy rate per ovulatory cycle 30%. Miscarriage rate 18.5%. 23 children were born including one set of twins. No serious side effects were recorded.
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http://dx.doi.org/10.3109/00016349409013436 | DOI Listing |
J Clin Med
December 2024
Fertisuisse, Clinic for Reproductive Medicine, 4600 Olten, Switzerland.
: Adolescence is the period of life between the ages of 10 and 19. This period is essentially dominated by puberty. The first menstruation, called menarche, occurs, on average, at the age of 12-13.
View Article and Find Full Text PDFJ Pediatr Adolesc Gynecol
December 2024
Penn State College of Medicine, Hershey, PA, USA; Division of Adolescent Medicine.
Study Objective: Anorexia nervosa (AN) and atypical anorexia nervosa (AAN) are eating disorders (EDs) characterized by extreme restriction of energy intake. However, in contrast to AN, those with AAN are not underweight. Although individuals with either AN or AAN can experience associated functional hypothalamic amenorrhea (FHA) that may prompt them to seek gynecological care, little is known about OBGYNs' knowledge and approach to these patients; this study sought to fill this gap.
View Article and Find Full Text PDFJ Turk Ger Gynecol Assoc
December 2024
Department of Gynecology, Hospital Primavera, Aracaju, Brazil.
The Coronavirus disease-19 (COVID-19) pandemic was declared in March 2020 by the World Health Organization. The severe acute respiratory syndrome-coronavirus-2 virus enters host cells through angiotensin-converting enzyme 2 receptors and transmembrane serine protease type II that are expressed in pulmonary alveoli, as well as in hepatocytes, endothelium, ovaries, uterus, vagina, thyroid, and other tissues. In addition to viral injury, the COVID-19 pandemic, through protective measures such as social isolation and lockdown, has promoted a scenario of psychosocial stress, especially in women.
View Article and Find Full Text PDFMinerva Obstet Gynecol
December 2024
Department of Medicine, Surgery and Dentistry, Schola Medica Salernitana, University of Salerno, Baronissi, Salerno, Italy.
Background: Intensive physical activity and rigid dietary regimes can act as modifiers of neuroendocrine axes in women, inducing hormonal disorders and related menstrual irregularities such as functional hypothalamic amenorrhea (FHA). It would be important to evaluate if such disturbances may worsen female fertility. The aim of this study was to evaluate ovarian reserve markers and neuroendocrine axis in young military academy female cadets with years of training and occurrence of FHA.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!