Studies of blood serum samples from Asian mice from a natural focus of tick-borne encephalitis (TBE) in the Krasnoyarsk district, in which agent strains of medium peripheral activity for white mice predominated, in the hemagglutination inhibition test have given negative results. At the same time murine sera were detected with nonspecific inhibitors to TBE virus in low titers (1:10 to 1:20), this being confirmed by enzyme immunoassay. Of the tested in 1988-1991 1047 mice of 11 species the share of sera with nonspecific inhibitors (and, consequently, positive ones) has made up 3.3 +/- 1.9/0.0 for asian mice (6.2 +/- 3.3/0.0 for males and 0.0/0.0 females), 1.4 +/- 1.4/2.8 +/- 2.0 in striped field mice (0.0/0.0 males and 3.2 +/- 3.2/6.4 +/- 4.5 females), and 0.5 +/- 0.3/5.7 +/- 1.0 in red-backed mice (0.3 +/- 0.3/6.3 +/- 1.4 males and 0.7 +/- 0.5/5.1 +/- 1.3 females).
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