The paper reports the results achieved on the treatment of 193 patients with polyetiological cochleovestibulopathy (PC). Clinical and experimental findings urge a strict differential-diagnostic approach to PC treatment. Original techniques are provided on endaural pharmacophysical management of the labyrinth disorders.
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Cureus
December 2024
Oral and Maxillofacial Radiology, Henry M. Goldman School of Dental Medicine, Boston, USA.
A dentigerous cyst (DC) is the most common developmental cystic lesion of the jaws. Histologically, these cysts derive from the odontogenic epithelium that includes the reduced enamel epithelium, epithelial cell rests of Serres, and epithelial cell rests of Malassez. Radiographically, DCs are usually presented as well-defined radiolucencies associated with the crown of an unerupted tooth at the level of the cementoenamel junction (CEJ).
View Article and Find Full Text PDFInt J Mol Sci
January 2025
The Azrieli Faculty of Medicine, Bar-Ilan University, Safed 1311502, Israel.
Autoimmune diseases are complex conditions characterized by immune-mediated tissue damage and chronic inflammation. Protease-activated receptor 2 (Par2) has been implicated in these diseases, exhibiting dual roles that complicate its therapeutic potential. This review examines the perplexing functions of Par2, which promotes inflammation through immune cell activation while facilitating tissue healing in damaged organs.
View Article and Find Full Text PDFFront Med (Lausanne)
December 2024
Department of Cardiology, General Hospital of Central Theater Command of the People's Liberation Army, Wuhan, China.
is often considered a complex associated with a healthy plant-based diet that acts as a "probiotic" throughout the body's entire digestive tract from the mouth to the anus. Previous studies have not reported that this "probiotic" colonizing the human body could cause severe pneumonia. This case report describes a 56-year-old healthy female worker with gum pain followed by fever.
View Article and Find Full Text PDFRadiologie (Heidelb)
January 2025
Klinik für Diagnostische und Interventionelle Neuroradiologie, Universitätsklinikum des Saarlandes, Kirrberger Str., 66424, Homburg, Deutschland.
The history of stroke dates back to antiquity, where it was first described as "apoplexia" in Hippocratic writings. For centuries, understanding of the pathology was limited, based on Galen's theories and humoral pathology. Significant advances were made by Islamic scholars who expanded the knowledge and addressed existing contradictions.
View Article and Find Full Text PDFCell Commun Signal
January 2025
Department of Immunology, University of Connecticut School of Medicine, Connecticut, Farmington, 06030, USA.
Background: Neutrophils are the most abundant leukocytes in human blood, and their recruitment is essential for innate immunity and inflammatory responses. The initial and critical step of neutrophil recruitment is their adhesion to vascular endothelium, which depends on G protein-coupled receptor (GPCR) triggered integrin inside-out signaling that induces β2 integrin activation and clustering on neutrophils. Kindlin-3 and talin-1 are essential regulators for the inside-out signaling induced β2 integrin activation.
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