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In addition to conventional outpatient treatment 165 psoriasis patients underwent hemosorption (100 cases) or plasmapheresis (65 cases). The efferent methods used proved beneficial in 99 (60%) of the patients that got to have normal hemograms, reduced CIC and middle molecular weight peptides levels in blood. The response depended on the disease duration irrespectively of the method of efferent treatment. The remission (1-2 years) was achieved in 79 (48%) of the patients treated who developed neither side effects no complications. Compared to controls on hospital routine therapy, a mean decrease in treatment duration made 10 +/- 4 days. Efferent outpatient treatment of psoriasis is recommended for patients with torpid course of the disease and for those who is ill not longer than 5 years.

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