[The prevalence of the main risk factors among probands who have had a myocardial infarct at a young age and among their relatives (based on family registry data in Bishkek and Novosibirsk)].

Macrofocal or transmural myocardial infarction at the age under 50 in probands served the criterion for selection of 136 families in Bishkek and Novosibirsk (66 Kirghiz and 70 Russian families, respectively). Main risk factors in probands and their families were determined according to WHO methodological recommendations. Essential hypertension was more prevalent in probands and their families in Bishkek, while hypercholesterolemia was more common in Novosibirsk families. Smoking was documented in Bishkek and Novosibirsk probands in equal proportions, though there were more smokers among probands' sons in Bishkek. Overweight occurred with equal frequency in probands' wives and daughters in both cities, but in probands and their sons in Novosibirsk this risk factor appeared more prevalent. Novosibirsk cases of reduced levels of high-density lipoproteins cholesterol and triiodothyronine, elevated concentrations of apolipoprotein B and immunoreactive insulin outnumbered those in Bishkek.