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Unraveling the Mysteries of Ameloblastoma in African Population: A Comprehensive Analysis of 371 Cases from Clinical, Radiological, and Histopathological Perspectives.
Head Neck Pathol
January 2025
Department of Oral Medicine and Radiology, King George's Medical University, Lucknow, India.
Objective: To analyze the frequency, clinical, histopathological, and radiological characteristics of ameloblastoma in Nigeria over the course of two decades.
Study Design: A retrospective analysis was conducted on 371 cases at a Nigerian university hospital between 2000 and 2023. Age, gender, site, histological variants, tumor size and duration were analyzed.
Surrogate Immunohistochemical Markers of Proliferation and Embryonic Stem Cells in Distinguishing Ameloblastoma from Ameloblastic Carcinoma.
Head Neck Pathol
October 2024
Department of Oral and Maxillofacial Pathology, Faculty of Health Sciences, University of Pretoria, Pretoria Oral Health Care Centre, Office 6-11, Corner of Steve Biko and Dr Savage Roads, Pretoria, 0084, South Africa.
Purpose: The current study aimed to investigate the use of surrogate immunohistochemical (IHC) markers of proliferation and stem cells to distinguish ameloblastoma (AB) from ameloblastic carcinoma (AC).
Methods: The study assessed a total of 29 ACs, 6 ABs that transformed into ACs, and a control cohort of 20 ABs. The demographics and clinicopathologic details of the included cases of AC were recorded.
Prevalence of Ameloblastoma in Sub-Saharan Africa: A systematic review and meta-analysis.
J Stomatol Oral Maxillofac Surg
August 2024
Continuum Oral Health Inc., 61 Lincoln Street, Framingham, MA 01702, United States.
Introduction: Ameloblastoma is the most common odontogenic tumor (OT) accounting for about 1- 3 % of all tumors and tumor-like lesions of the head and neck region. Contrasting reports from documented studies have observed that the relative frequency of ameloblastomas is higher in the black population as compared to Caucasians. This is a systematic review and meta-analysis of Sub-Sahara African prevalence of Ameloblastoma.
View Article and Find Full Text PDFPediatric Odontogenic and Maxillofacial Bone Pathology: A Global Analysis.
J Craniofac Surg
May 2022
Department of Plastic Surgery, University of Kansas Medical Center.
Background: Although pathology in the maxillary and mandibular bones is rare in young patients, the differential diagnosis is broad. The World Health Organization (WHO) updated its classification of maxillofacial bone pathology in 2017. Using these updated guidelines, a systematic review of common maxillofacial bone lesions in the pediatric population was performed.
View Article and Find Full Text PDFDescriptive Epidemiology of Odontogenic Tumors in Nigeria: An African Oral Pathology Research Consortium Multicenter Study.
Niger J Clin Pract
December 2020
Department of Oral and Maxillofacial Pathology, Faculty of Dentistry, University of the Western Cape and Tygerberg Hospital; Division of Dermatology, Department of Medicine, Faculty of Health Sciences and Groote Schuur Hospital, University of Cape Town, Cape Town, South Africa.
Background: Many studies have investigated the burden of odontogenic tumor (OT) in Nigeria; however, the true burden and prevalence of these lesions are not known because these studies are based on a center/region.
Aims: Hence, the aim of this study is to evaluate the true burden of OTs in Nigeria, using a multicenter approach.
Materials And Methods: This is a 10-year retrospective cross-sectional study of OT seen in eight tertiary health institutions in different geographic locations in Nigeria.
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