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Efficacy of Pericapsular Nerve Group (PENG) block in preoperative rehabilitation (Prehabilitation) for patients with femoral neck fractures: study protocol for a randomized, placebo-controlled, double-blinded trial.
BMC Anesthesiol
November 2024
Department of Anesthesiology, Kameda Medical Center, Kamogawa, Japan.
Article Synopsis
- The study investigates the effectiveness of a pericapsular nerve group (PENG) block in improving prehabilitation for patients with femoral neck fractures scheduled for hip arthroplasty, focusing on pain management without sacrificing motor function.
- It will enroll 100 patients with specific fracture types, randomly assigning them to receive either a PENG block or a placebo before beginning a structured prehabilitation program aimed at enhancing mobility and surgical outcomes.
- The main measurements will include how many patients complete the prehabilitation, their pain levels, and various postoperative outcomes like bleeding and mobility scores, comparing those who received surgery within 48 hours to those who did not.
Venetoclax plus decitabine as a bridge to allogeneic haematopoietic stem-cell transplantation in older patients with acute myeloid leukaemia (VEN-DEC GITMO): final report of a multicentre, single-arm, phase 2 trial.
Lancet Haematol
November 2024
Unit of Hematology and Stem Cell Transplantation, Ospedale San Raffaele, University Vita-Salute San Raffaele, Milan, Italy.
Background: Access to allogeneic haematopoietic stem-cell transplantation (HSCT) remains challenging for older patients (aged >60 years) with acute myeloid leukaemia. We aimed to evaluate the efficacy of venetoclax plus decitabine as first-line therapy and bridge to transplantation in this patient population.
Methods: This multicentre, single-arm, phase 2 trial was conducted in 20 Gruppo Italiano Trapianto Midollo Osseo (GITMO) centres in Italy.
Dissipation and dietary risk assessment of fluoxapiprolin (and its metabolites) residues in cucumber and tomato samples under field conditions.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess
October 2024
Pesticide Residue Laboratory, AINP on Pesticide Residues, Anand Agricultural University, Anand, India.
The present study was undertaken to understand the dissipation behaviour/kinetics of fluoxapiprolin and its metabolites in cucumber and tomato under field conditions. A QuEChERS based extraction method followed by liquid chromatography coupled to mass spectrometry (LC-MS/MS) analysis showed that all method validation parameters were within the acceptable range as per international standards with a limit of quantitation (LOQ) of 0.01 mg kg for all analytes.
View Article and Find Full Text PDFBleaching effect on bonding performance of composite to enamel.
Microsc Res Tech
October 2024
Department of Medical Statistics and Informatics, Faculty of Medicine, University of Nis, Nis, Serbia.
This study aimed to assess the effects of dental bleaching on the immediate shear bond strength (SBS) of composite to enamel. Different bleaching methods and time intervals between bleaching and composite restoration were examined. A total of 45 enamel specimens were divided into three groups (n = 15) based on the applied bleaching protocol: in-office (A), at-home (B), and unbleached control (C).
View Article and Find Full Text PDFPhosphodiesterase type 5 inhibitors as treatment for erectile dysfunction: a webinar-based poll unveiling perceptions of healthcare professionals.
J Comp Eff Res
July 2024
Professor of Cardiology, King Fahad cardiac center, King Khaled university hospital, King Saud university, Riyadh, Saudi Arabia- National heart institute, Cairo, Egypt.
Erectile dysfunction (ED) is marked by a recurring incapacity to achieve or uphold a satisfactory erection during sexual activities. The study aims to increase awareness about male reproductive health, dispel misconceptions about ED and encourage physician-patient discussions. A live online poll was conducted during a 3-day webinar titled "Turning the Tide of Men's Health" organized by Viatris™ in collaboration with the Saudi Society of Family and Community Medicine and attended by healthcare professionals (HCPs) from diverse specialties.
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