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Prevalence and factors associated with potential clinically significant drug-drug interactions in patients with cardiovascular diseases at hospital admission.
Acta Pharm
December 2024
Department of Clinical Pharmacy, University Hospital Dubrava, 10000 Zagreb Croatia.
Cardiovascular diseases (CVDs) are the leading cause of mortality and morbidity globally. It is estimated that 17.9 million people died from CVDs in 2019, which represents 32 % of all deaths worldwide.
View Article and Find Full Text PDFChronic disease risk factors among hospital employees: A cross-sectional study in Türkiye.
PLoS One
January 2025
Employee Health Department, General Directorate of Public Health, Ministry of Health, Ankara, Türkiye.
Introduction: Chronic diseases have become a significant public health problem with the prolongation of human life. There are four main behavioral risk factors for mortality. This study evaluated the significant risk factors for chronic diseases in university hospital employees.
View Article and Find Full Text PDFEvaluating Harms Associated with Prolonged Antibiotic Duration of Therapy in Community Dwelling Older Adults: A Cohort Study using Instrumental Variable Analysis.
Clin Infect Dis
December 2024
Public Health Ontario; Dalla Lana School of Public Health, University of Toronto; Unity Health Toronto.
Background: Shorter courses of antibiotic therapy are increasingly recommended to reduce antibiotic exposure. However quantifying the real-world impact of duration of therapy is hindered by bias common in observational studies. We aimed to evaluate the harms and benefits of longer versus shorter duration of therapy in older adults.
View Article and Find Full Text PDFBiomarkers.
Alzheimers Dement
December 2024
Weill Cornell Medicine, New York, NY, USA; St Vincent's Hospital, Melbourne, VIC, Australia.
Background: Postoperative delirium (POD) is a serious complication of surgery associated with prolonged hospitalisation, long-term cognitive decline, dementia and mortality. There is increasing evidence that electroencephalography (EEG) monitoring may reduce the incidence of POD, however, the best method for achieving this is unclear.
Method: This presentation will present the results of a multicentre randomised clinical trial of 515 at-risk patients undergoing major surgery from 8 centres in 3 countries who were assessed for POD for 5 days postoperatively.
Emergency medical services level of training is associated with mortality in trauma patients: A combined prehospital and in hospital database analysis.
J Trauma Acute Care Surg
January 2025
From the Department of Surgery (J.H., K.S., G.S.C., C.T., L.R., G.B.); School of Public Health (A.B., O.H., A.S., S.M.); Hennepin Healthcare (S.K.); Department of Emergency Medicine (S.K., M.A.P.); and Hennepin Healthcare, Department of Emergency Medicine (M.A.P.), Minneapolis, Minnesota.
Background: There is conflicting evidence regarding emergency medical service (EMS) provider level of training and outcomes in trauma. We hypothesized that advanced life support (ALS) provider transport is associated with lower mortality compared with basic life support transport.
Methods: We performed secondary analysis of a combined prehospital and in-hospital database of trauma patients utilizing ESO electronic medical records from 2018 to 2022.
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