Sixty-four strains of Leishmania of canine origin, 61 visceral and three cutaneous, were isoenzymatically examined. These were collected from 23 sites in the Granada region in southern Spain. Starch gel was used in electrophoresis and a total of 15 enzymes were studied. All of the visceral strains and two of the cutaneous ones were identified as L. infantum zymodeme GR-1 (= MON-1). The third cutaneous strain was of a different zymodeme, belonging to the same complex but differing in the glucose-6-phosphate dehydrogenase (= 105) enzyme. This zymodeme has been named GR-16 and is equivalent to L. infantum MON-105; it has not been previously reported in dogs or any other animal reservoir.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.4269/ajtmh.1994.50.758 | DOI Listing |
Geroscience
January 2025
Pennington Biomedical Research Center, 6400 Perkins Road, Baton Rouge, LA, 70808, USA.
Declines in physical and cognitive function are common in older adults. The circulating enzyme glycosylphosphatidylinositol (GPI)-specific phospholipase D1 (GPLD1) is elevated after exercise and has been associated with improved cognitive function when administered to aged mice. The purpose of this study was to investigate the relationship between GPLD1 and both cognitive function and brain structure/function in older adults with either high or low levels of physical activity.
View Article and Find Full Text PDFBiol Sport
January 2025
PROFITH (PROmoting FITness and Health through Physical Activity) Research Group, Sport and Health University Research Institute (iMUDS), Department of Physical and Sports Education, Faculty of Sport Sciences, University of Granada, Granada, Spain.
Increasing physical activity (PA) is recognised as an efficacious approach for preventing and treating cardiometabolic diseases. Recently, the composition of microorganisms living within the gut has been proposed as an important appropriate target for treating these diseases. Whether PA is related to faecal microbiota diversity and composition in humans remains to be ascertained.
View Article and Find Full Text PDFSci Data
January 2025
LoyolaBehLab, Universidad Loyola Andalucía, Córdoba, Spain.
This dataset originates from TeensLab, a consortium of Spanish Universities dedicated to behavioral research involving Spanish teenagers. The dataset contains data from 33 distinct educational institutions across Spain, accounting for a total of 5,890 students aged 10 to 23 (M = 14.10, SD = 1.
View Article and Find Full Text PDFNeurol Neuroimmunol Neuroinflamm
March 2025
Hospices Civils de Lyon, Service de Neurologie, Sclérose en Plaques, Pathologies de la Myéline et Neuro-Inflammation-Hôpital Neurologique Pierre Wertheimer, Bron Cedex.
Objectives: To characterize the serum cytokine profile in myelin oligodendrocyte glycoprotein antibody-associated disease (MOGAD) at onset and during follow-up and assess their utility for predicting relapses and disability.
Methods: This retrospective multicentric cohort study included patients aged 16 years and older meeting MOGAD 2023 criteria, with serum samples collected at baseline (≤3 months from disease onset) and follow-up (≥6 months from the baseline), and age-matched and time to sampling-matched patients with multiple sclerosis (MS). Eleven cytokines were assessed using the ELLA system.
Physiol Genomics
January 2025
Department of Biochemistry and Molecular Biology, Faculty of Sciences, University of Granada, Granada, Spain; Instituto de Investigación Biosanitaria ibs.GRANADA, Granada, Spain.
We examined the effects of a 20-week exercise intervention on whole-blood genome-wide DNA methylation signature and its association with the exercise-induced changes in gene expression profiles in boys and girls with overweight/obesity (OW/OB). Twenty-three children (10.05 ± 1.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!