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All the polymeric composite restorative resins shrink during polymerisation resulting in the development of tensile and/or shear stresses at the tooth/restoration interface. The major part of the contraction stresses develops within 15 minutes after the initiation of polymerisation but with the light activated resins it occurs within seconds after irradiation. The tensile stresses may disrupt the adhesive bonding of the restorative system to the cavity walls resulting in microleakage at the tooth/restoration interface. The properties of the restorative resins which include polymerisation shrinkage during hardening, differences in the coefficients of thermal expansion of the tooth and the restoration, and water sorption of the restoration on exposure to the oral environment, play an important role in determining the marginal gap dimensions and hence microleakage. Microleakage at the enamel/restoration interface has been eliminated by the acid etch technique provided that adequate enamel thickness is present. Microleakage at the dentine/restoration interface, however, is much more difficult to eliminate. None of the dentinal bonding restorative systems eliminates microleakage at the gingival margins of restorations that extend to or beyond the cementum/enamel junction. Microleakage is reduced by using an incremental restorative technique but is increased when the restored teeth are subjected to masticatory stress or occlusal loading. None of the dentinal bonding systems prevents the development of marginal gaps at the dentine/restoration interface when evaluated 10 minutes after placement of the restorations but hygroscopic expansion resulting from water or saline immersion results in a significant reduction in marginal gap dimensions. An increase in the cavosurface margins reduces marginal gap dimensions but it is not dependent on cavity depth.(ABSTRACT TRUNCATED AT 250 WORDS)
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Biostatistics
December 2024
Department of Biostatistics, Brown University, 121 South Main Street, Providence, RI 02903, United States.
Randomized controlled trials evaluating the diagnostic accuracy of a marker frequently collect information on baseline covariates in addition to information on the marker and the reference standard. However, standard estimators of sensitivity and specificity do not use data on baseline covariates and restrict the analysis to data from participants with a positive reference standard in the intervention arm being evaluated. Covariate-adjusted estimators for marginal treatment effects have been developed and been advocated for by regulatory agencies because they can improve power compared to unadjusted estimators.
View Article and Find Full Text PDFBMJ Open
March 2025
Department of Paediatrics, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Melbourne, Victoria, Australia.
Introduction: Early childhood education and intervention programmes can improve the developmental outcomes for priority groups of children. However, in Australia, a culturally responsive developmental outcome measure that has been validated for use with Aboriginal and Torres Strait Islander children is required to effectively evaluate impact.The Ages and Stages Questionnaire-Steps for Measuring Aboriginal Child Development (ASQ-STEPS) has been developed to fill this gap.
View Article and Find Full Text PDFEur J Dent
March 2025
Post-Graduate Program in Oral Sciences (Prosthodontics Units), Faculty of Dentistry, Universidade Federal de Santa Maria (UFSM), Santa Maria, Rio Grande do Sul, Brazil.
Objectives: To analyze the marginal/internal gap and the fatigue behavior of crowns made of two different materials, using four combinations of a digital workflow-two intraoral scanners (IOSs) and two milling machines.
Materials And Methods: Crowns were made considering three factors: IOS (a confocal microscopy-based scanner: TRIOS 3-TR; or a combination of active triangulation and dynamic confocal microscopy: Primescan-PS), milling machines (four-axis: CEREC MC XL-CR or five-axis: PrograMill PM7-PM), and restorative material (lithium disilicate-LD or resin composite-RC) ( = 10). The bonding surface of each crown was treated and bonded to each respective glass fiber-reinforced epoxy resin die using a dual-cure resin cement.
Eur J Dent
March 2025
Department of Dental Materials Science, Academic Centre for Dentistry Amsterdam (ACTA), Universiteit van Amsterdam and Vrije Universiteit, Amsterdam, North Holland, the Netherlands.
Objectives: This article evaluates the marginal and internal gap, interfacial volume, and fatigue behavior in computer-aided design-computer-aided manufacturing (CAD-CAM) restorations with different designs (crowns or endocrowns) made from lithium disilicate-based ceramic (LD, IPS e.max CAD, Ivoclar AG) or resin composite (RC, Tetric CAD, Ivoclar AG).
Materials And Methods: Simplified LD and RC crowns (-C) and endocrowns (-E) were produced ( = 10) using CAD-CAM technology, through scanning (CEREC Primescan, Dentsply Sirona) and milling (CEREC MC XL, Dentsply Sirona), and then adhesively bonded to fiberglass-reinforced epoxy resin.
Nanoscale
March 2025
Department of Chemistry, University of Florida, Gainesville, FL 32611, USA.
Conjugated polymers (CPs), characterized by alternating and π bonds, have attracted significant attention for their diverse structures and adjustable electronic properties. However, predicting the optical band gap (expgap) of CPs remains challenging. This study presents a rational model that integrates density functional theory (DFT) calculation with a data-driven machine learning (ML) approach to predict the experimentally measured expgap of CPs, using 1096 data points.
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