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Zebrafish ETS transcription factor Fli1b functions upstream of Scl/Tal1 during embryonic hematopoiesis.
Biol Open
March 2025
Department of Pathology and Cell Biology, USF Health Heart Institute, University of South Florida, Tampa, FL 33602, USA.
During embryonic development vascular endothelial and hematopoietic cells are thought to originate from a common precursor, the hemangioblast. An evolutionarily conserved ETS transcription factor FLI1 has been previously implicated in the hemangioblast formation and hematopoietic and vascular development. However, its role in regulating hemangioblast transition into hematovascular lineages is still incompletely understood.
View Article and Find Full Text PDFEffect of intermittent hemodialysis filtration mode on intradialytic hypotension and nutritional status in patients with end-stage renal disease.
Ther Apher Dial
March 2025
Nephrology Blood Purification Center, The First Medical Center, Chinese People's Liberation Army General Hospital, Beijing, China.
Introduction: This study aimed to investigate the effect of intermittent hemodialysis filtration mode (IHDF) on intradialytic hypotension and nutritional status in patients with end-stage renal disease (ESRD).
Methods: Patients with ESRD who underwent hemodialysis and were treated at our hospital from December 2021 to December 2023 according to the inclusion and exclusion criteria were selected and randomly assigned into two groups: the experimental group (patients received intermittent hemodialysis filtration mode treatment, n = 50) and the control group (patients received conventional maintenance hemodialysis treatment, n = 49). Subsequently, the participant characteristics, the treatment effect, the occurrence of intradialytic hypotension, the safety assessment, blood pressure indicators, and the nutritional status were compared between the two groups.
Developing and Implementing a Colorectal Cancer Screening Program in Uganda: Stakeholder Perceived Barriers and Opportunities.
Cancer Med
March 2025
Centre for Public Health, Queen's University Belfast, Belfast, UK.
Introduction: Colorectal cancer (CRC) incidence is increasing in Uganda. Despite this, and the disproportionately high burden of early onset and late-stage CRC cases, no CRC screening program exists in Uganda. To guide and inform future CRC prevention efforts, interviews with key stakeholders were undertaken to better understand the perceived barriers and opportunities relevant to the development and implementation of a CRC screening program in Uganda.
View Article and Find Full Text PDFPostoperative outcome of palatine tonsillectomy by tonsil pillar suture with knot-free suture.
Acta Otolaryngol
March 2025
Department of Otolaryngology, Toho University Omori Medical Centre, Tokyo, Japan.
Background: Postoperative haemorrhage following palatine tonsillectomy occurs in 5-14% of cases. Since 2021, our department has used knot suturing with 3-0 Vicryl, and from 2023, continuous suturing with the V-Loc closure device to reduce suture time. While knot suturing is reported to reduce postoperative bleeding and pain, no studies have compared outcomes between different suture methods.
View Article and Find Full Text PDFRecombinant PZ-Dependent Protease Inhibitor Mutant as a Novel Antithrombotic Agent: An Example of a Therapeutic Serpin.
Arterioscler Thromb Vasc Biol
March 2025
Université Paris Cité and Université Sorbonne Paris Nord, Inserm U1148-LVTS, France.
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