The benefits of Nd:YAG laser capsulotomy on visual performance were evaluated in 13 patients with after-cataract following extracapsular cataract extraction. Besides clinical evaluation we measured: visual acuity, letter contrast sensitivity with and without the presence of a circular glare source (glare angle: 8 degrees). Finally, the patients were asked to evaluate their subjective glare problems. In all patients, visual acuity had decreased markedly compared to measurements 2 months after cataract surgery. Before capsulotomy we observed impaired letter contrast sensitivity and increased intraocular light scatter compared to normals. Following capsulotomy, VA and contrast sensitivity both improved by a factor of 2. The subjective glare problems diminished, although most patients showed minor decreases in intraocular light scatter. The limited glare induced loss of letter contrast sensitivity, present before capsulotomy, remained after treatment. Our study indicates that after-cataract impairs resolution and contrast sensitivity without necessarily causing a marked increase in light scatter as measured at a large angle.
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http://dx.doi.org/10.1111/j.1755-3768.1994.tb02732.x | DOI Listing |
J Pathol Clin Res
January 2025
Department of Urology, University of Duisburg-Essen, Essen, Germany.
Distinct molecular subtypes of muscle-invasive bladder cancer (MIBC) may show different platinum sensitivities. Currently available data were mostly generated at transcriptome level and have limited comparability to each other. We aimed to determine the platinum sensitivity of molecular subtypes by using the protein expression-based Lund Taxonomy.
View Article and Find Full Text PDFFront Parasitol
September 2023
Laboratório de Parasitologia Médica (LIM-46), Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo (FMUSP), São Paulo, Brazil.
Background: Evaluating the effectiveness of Chagas disease treatment poses challenges due to the lack of biomarkers for disease progression and therapeutic response. In this study, we aimed to assess the clearance of Trypanosoma cruzi ( parasites in a group of benznidazole (BNZ)-treated chronic Chagas disease patients using high-sensitivity quantitative PCR (qPCR) and track antibody levels through a semiquantitative chemiluminescent assay.
Methods: A total of 102 seropositive patients with previous PCR-positive results were enrolled in the study.
Transl Cancer Res
December 2024
Department of Radiology, Shanghai Chest Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Background: The pathological sub-classification of lung cancer is crucial in diagnosis, treatment and prognosis for patients. Quick and timely identification of pathological subtypes from imaging examinations rather than histological tests could help guiding therapeutic strategies. The aim of the study is to construct a non-invasive radiomics-based model for predicting the subtypes of lung cancer on brain metastases (BMs) from multiple magnetic resonance imaging (MRI) sequences.
View Article and Find Full Text PDFClin Ophthalmol
January 2025
Department of Ophthalmology, Affiliated Hospital of North Sichuan Medical College, Nanchong, Sichuan Province, 637000, People's Republic of China.
Objective: To assess the visual quality in patients with primary angle-closure glaucoma (PACG) complicated by cataracts after cataract phacoemulsification with intraocular lens (IOL) implantation and goniosynechialysis, and to explore the relationship between pupil size and visual quality.
Methods: A retrospective, non-randomized study was conducted, including 65 PACG patients (75 eyes) who underwent cataract surgery with IOL implantation and goniosynechialysis from July 2021 to June 2023, as well as a control group of cataract-only patients. Visual quality was evaluated using objective and subjective methods at least 3 months postoperatively.
Biomed Opt Express
January 2025
Center for Visual Science, The Institute of Optics, Flaum Eye Institute. University of Rochester, Rochester, NY, USA.
An intraocular lens (IOL) replaces the natural crystalline lens during cataract surgery, and although the vast majority of implants have simple optics, "advanced technology" IOLs have multifocal and extended depth of focus (EDOF) properties. Optical concepts are evaluated here, with image contrast, focal range, and unwanted visual phenomena being the primary concerns. Visual phenomena with earlier bifocal diffractive lenses led to alternative diffractive designs (trifocals, etc.
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