The examination covered 1191 lymphedema patients (635 primary and 536 secondary disease cases). Hypothyroidism-like thyroid dysfunction was found in 80% of patients with primary lymphedema. Measurements of thyroid hormones confirmed the above findings. It is hold that lymphedema patients should undergo the thyreoidin test and combined treatment including thyroid hormone therapy.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Endothelial cell alterations in capillaries of adipose tissue from patients affected by lipedema.
Obesity (Silver Spring)
March 2025
Department of Experimental and Clinical Medicine, Center of Obesity, Università Politecnica delle Marche (Polytechnic University of Marche), Ancona, Italy.
Objective: This study aimed to evaluate adipose tissue of lipedema patients.
Methods: Gluteo-femoral (affected area) and interscapular (nonaffected area) adipose tissue from 10 lean patients affected by lipedema stage 1 to 2 was studied and compared with tissue from 10 patients with obesity and 12 lean patients.
Results: The main features were alterations of capillaries with wall thickening (p ≤ 0.
Generation of human induced pluripotent stem cell line from peripheral blood of patient with lymphedema-distichiasis syndrome.
Stem Cell Res
March 2025
Department of Medical Biotechnology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Kraków, Poland. Electronic address:
Lymphedema-distichiasis syndrome (LDS) is an autosomal dominant genetic disorder associated with mutations in forkhead box C2 (FOXC2) gene, critical for lymphatic endothelial cell (LEC) differentiation. LDS patients suffer from swelling of limbs (lymphedema) due to excessive lymph accumulation and are characterized by the presence of additional row of eyelashes (distichiasis). Here, we generated human induced pluripotent stem cells (hiPSCs) from LDS patient-derived peripheral blood mononuclear cells (PBMCs).
View Article and Find Full Text PDFBreaking the cycle: Addressing the drucebo effect in lymphedema care.
Phlebology
March 2025
Department of Biomedical and Neuromotor Sciences, Alma Mater Studiorum, University of Bologna, Bologna, Italy.
The drucebo effect, a lesser-known counterpart to the nocebo effect, arises from negative perceptions specifically related to medical interventions and healthcare settings. This phenomenon can significantly influence the management of lymphedema, a chronic and often debilitating condition characterized by fluid retention and tissue swelling. The drucebo effect not only exacerbates symptom perception but also negatively impacts adherence to therapy and overall patient prognosis.
View Article and Find Full Text PDFObjectifying Clinical Outcomes After Lymphaticovenous Anastomosis and Vascularized Lymph Node Transfer in the Treatment of Extremity Lymphedema: A Systematic Review and Meta-Analysis.
Microsurgery
March 2025
Department of Plastic and Reconstructive Surgery, University Medical Center Utrecht, Utrecht, the Netherlands.
Background: Upper extremity lymphedema (UEL) and lower extremity lymphedema (LEL) can develop as a result of lymph node dissection in the treatment of various malignancies. While emerging microsurgical interventions using lymphaticovenous anastomosis (LVA) and vascularized lymph node transfer (VLNT) show promising outcomes for patients with lymphedema, the best approach to implementing the two procedures remains to be defined. This systematic review and meta-analysis provide a comprehensive overview of published literature on the clinical improvement of extremity lymphedema in patients who undergo either LVA, VLNT, or a combined microsurgical procedure.
View Article and Find Full Text PDFA Case of Postoperative Lymphatic Ascites in Endometrial Cancer Spontaneously Resolving After Approximately One Year of Watchful Waiting.
Cureus
February 2025
Department of Obstetrics and Gynecology, Shiga University of Medical Science, Otsu, JPN.
Postoperative lymphatic ascites following lymph node dissection for gynecologic malignancies is not uncommon, although in most cases it resolves spontaneously within two to three weeks, or at most within four months. We present the case of a 73-year-old woman who underwent total hysterectomy with bilateral salpingo-oophorectomy and pelvic and para-aortic lymph node dissection for endometrial cancer. She subsequently developed a large volume of ascites, which was diagnosed as lymphatic ascites based on biochemical analysis of the ascitic fluid, cytological examination, and CT findings.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!