We report a 35 year old male, human immunodeficiency virus (HIV)-infected patient with acquired immune deficiency syndrome (AIDS), who presented with rapidly progressive pulmonary Kaposi's sarcoma. The tumour regressed with treatment with liposomal daunorubicin and remained in partial remission until the patient died 12 months later from complications of HIV infection. Liposomal daunorubicin may be a safe and effective alternative to the treatment protocols in current use for pulmonary Kaposi's sarcoma.
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http://dx.doi.org/10.1183/09031936.94.07040824 | DOI Listing |
Zhonghua Jie He He Hu Xi Za Zhi
January 2025
Department of Organ Transplantation, the First Affiliated Hospital of Guangzhou Medical University, State Key Laboratory of Respiratory Disease & National Clinical Research Center for Respiratory Disease, Guangzhou510120, China.
To investigate the clinical features, diagnosis, and treatment of pulmonary Kaposi sarcoma (KS) after lung transplantation. A case of pulmonary KS after bilateral lung transplantation was retrospectively analyzed. Two key words "Kaposi sarcoma" and "lung transplant*" were used to search for relevant literature in SinoMed, Wanfang Data, CNKI, PubMed, Embase, Cochrane Library and Web of Science, with a cut-off date of July 31, 2024.
View Article and Find Full Text PDFCureus
October 2024
Department of Internal Medicine, Medical University of South Carolina, Charleston, USA.
Kaposi sarcoma (KS) is a soft tissue tumor primarily occurring in immunosuppressed patients and, although it has been described, dissemination of KS is rare. This case involves a patient with acquired immunodeficiency syndrome (AIDS) and biopsy-proven cutaneous KS presenting with hematemesis suspected due to gastrointestinal involvement in whom endoscopy with biopsy was contraindicated due to dual antiplatelet therapy (DAPT) and the hypervascular nature of KS tumors. Alternatively, the diagnosis was made via macroscopic findings on bronchoscopy, which demonstrated neovascular lesions, confirming visceral KS.
View Article and Find Full Text PDFAm J Transplant
November 2024
Section of Hematology, Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, AOU Modena, Modena, Italy.
mBio
December 2024
Department of Cancer Biology and Infection Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.
EClinicalMedicine
July 2024
Institute for Healthcare Management and Research, University of Duisburg-Essen, Thea-Leymann-Str. 9, Essen, Germany.
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