Evening primrose oil was given through a intragastric catheter in dose of 50 mg/kg day for 10 days to pregnant (8 animals) and nonpregnant (8 animals) rabbits. Control groups contained 8 pregnant and 8 nonpregnant animals. In the acute experiment we estimated directly (intraarterially) basal blood pressure and pressor response to angiotensin II (A II). The systolic and diastolic response to A II was significantly lower in pregnant rabbits which received evening primrose oil compared to control group. No significant effect was found in the nonpregnant groups. Basal (before A II) systolic and diastolic blood pressure did not differ between the treated and untreated subject in each group.

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