Several methods for the evaluation of hair growth have been reported; however, none of the hitherto reported methods are satisfactory as unbiased double blind studies to evaluate the efficacy of hair growth agents. In the present paper, we describe quantitative evaluation methods for hair growth by measuring the anagen ratio and hair diameters in 56 Japanese subjects aged 23-56 for 3 years. The average anagen ratio decreased by 3.8% in 3 years. The average hair diameters showed a statistically significant decrease each year totalling 3.4 microns. Subjects were sorted according to their anagen ratio into 4 groups. Each group showed different distribution patterns of hair diameters. The higher anagen ratio group has a high frequency peak at thicker hair diameters and the lower anagen ratio group has a high frequency peak at thinner hair diameters. The number of thicker hairs decreased and the high frequency peak shifted to thinner hair diameters in 3 years. These methods are useful to evaluate both the progression of male pattern baldness and the effects of hair growth agents with double blind studies in an unbiased quantitative fashion.
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http://dx.doi.org/10.1016/0923-1811(94)90044-2 | DOI Listing |
Cureus
December 2024
Medical Affairs, Dr. Reddy's Laboratories Ltd., Hyderabad, IND.
Background Toothbrush manufacturers commonly use bristle materials such as nylon, polybutylene terephthalate, polypropylene, polyethylene terephthalate, boar hair, bamboo, carbon fiber, silicone, polylactic acid, or their modifications such as Curen. Nylon filaments have long been demonstrated to be durable and are widely used, but not much is known regarding the performance of Curen filaments compared to nylon filaments. This in vitro study compared the stiffness, abrasion potential, abrasion resistance, and bristle surface changes of Curen and nylon filaments.
View Article and Find Full Text PDFActa Dermatovenerol Croat
November 2024
Takayuki Suyama, MD, PhD, Department of Dermatology, Dokkyo Medical University Saitama Medical Center, 2-1-50 Minami-koshigaya, Koshigaya, Saitama, 343-8555, Japan; ORCID ID: 0000-0002-6986-411X.
Cystic basal cell carcinoma (BCC) is a rare subtype of BCC (1). Histologically, it is usually characterized by multiple small cysts without a clinical cystic appearance (2). Herein, we report an unusual case of cystic BCC with a large vulvar cyst.
View Article and Find Full Text PDFJ Biomech
December 2024
Office of Science and Engineering Laboratories, Center for Devices and Radiological Health, U.S. Food and Drug Administration, United States of America.
Medical image-based diagnostic techniques have become increasingly common in the clinic. Estimating fractional flow reserve in coronary stenoses from medical image data is among the most prominent examples. The modeling techniques used in these clinical tools require rigorous experimental validation yet there is currently no standardized, public toolset to help assess model credibility.
View Article and Find Full Text PDFNat Commun
January 2025
Bernstein Center for Computational Neuroscience Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Understanding vibrissal transduction has advanced by serial sectioning and identified afferent recordings, but afferent mapping onto the complex, encapsulated follicle remains unclear. Here, we reveal male rat C2 vibrissa follicle innervation through synchrotron X-ray phase contrast tomograms. Morphological analysis identified 5% superficial, ~32 % unmyelinated and 63% myelinated deep vibrissal nerve axons.
View Article and Find Full Text PDFInt J Dermatol
January 2025
Department of Dermatology, Warsaw University of Medicine, Warsaw, Poland.
Background: Afro-textured hair exhibits distinct physicochemical properties with possible variations in measurable hair parameters. Standardized documentation of trichoscopic norms of afro-textured hair in indigenous Africans is notably lacking.
Methods: A cross-sectional study involving 122 South Africans of both genders of African ancestry (mean age 20.
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