It was found that 229 out of 230 strains of pseudotuberculosis microbes tested were sensitive to aminoglycosides, such as streptomycin, monomycin, neomycin, kanamycin and gentamicin. The MIC did not exceed 50 gamma/ml. One strain of J. pseudotuberculosis was multiresistant to streptomycin, tetracycline, levomycetin and penicillin. The above aminoglycosides (streptomycin, monomycin, kanamycin and gentamicin) were active in the treatment of albino mice with experimental pseudotuberculosis.
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Pol J Vet Sci
June 2024
Department of Surgery, Faculty of Veterinary Medicine, University of Siirt, Kezer Campus, Veysel Karani District, University Street, Siirt/Türkiye.
In this study, a total of 32 Trueperella pyogenes strains isolated from different disease specimens in cattle, sheep and goats were examined. Antimicrobial susceptibility of the isolates to 10 antimicrobials were determined using the E-test method and MIC values of the antimicrobials were investigated. The genes that play a role in the antimicrobial resistance or virulence of T.
View Article and Find Full Text PDFSci Rep
December 2024
Infettare Research Group, School of Medicine, Universidad Cooperativa de Colombia, Calle 50 No. 40-74, Medellín, Colombia.
Bacterial resistance, a global public health concern prioritized by the World Health Organization, is particularly alarming in Staphylococcus aureus and Escherichia coli. Urgently addressing this, the search for new antibiotics has turned to plant essential oils. Our study focused essential oils derived from Colombian plants Croton killipianus, Croton smithianus, Croton leptostachyus, Croton hondensis, and Croton gossypiifolius.
View Article and Find Full Text PDFHealth Sci Rep
December 2024
Department of Microbiology School of Medicine, Zabol University of Medical Sciences Zabol Iran.
Background And Aims: (), included in the World Health Organization's list of critical priority pathogens, is considered a serious threat to public health. The present study aims to investigate the prevalence of virulence-associated and aminoglycoside resistance genes in clinical isolates of .
Methods: This cross-sectional study was carried out on 88 clinical isolates of .
Animals (Basel)
December 2024
Veterinary Epidemiology Unit, Department of Internal Medicine, Reproduction and Population Medicine, Faculty of Veterinary Medicine, Ghent University, Salisburylaan 133, 9820 Merelbeke, Belgium.
Pakistan has a large, intensive broiler production industry, where antimicrobials are extensively used for both therapeutic and prophylactic purposes. Monitoring antimicrobial use (AMU) at the farm level is crucial to guide interventions for antimicrobial stewardship. The objective of this study was to comprehensively quantify AMU on commercial broiler farms in Pakistan using different metrics.
View Article and Find Full Text PDFHealth Sci Rep
December 2024
Molecular and Cell Biology Research Centre, Faculty of Medicine Mazandaran University of Medical Sciences Sari Iran.
Background And Aims: Overexpression of MexXY-OprM efflux pump causes resistance to aminoglycosides in . We aimed to investigate the relationship between resistance to aminoglycosides and the MexXY-OprM expression level in clinical isolates without and after treatment with curcumin and/or phenylalanine-arginine-beta-naphthylamide (PAβN) as the efflux pump inhibitors.
Methods: We collected 100 clinical isolates from hospitalized patients.
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