Aspergillosis of the larynx.

J Laryngol Otol

Royal National Throat, Nose and Ear Hospital, London.

Published: October 1994

AI Article Synopsis

  • Primary laryngeal infection with Aspergillus is quite rare and typically occurs in immunocompromised individuals, often as part of a broader respiratory infection.
  • In patients with a strong immune system, laryngeal aspergillosis may simply indicate colonization, meaning no systemic antifungal treatment is necessary.
  • A case study illustrates a 62-year-old man with hoarseness, where direct laryngoscopy and biopsy conclusively diagnosed him with aspergillosis, highlighting crucial symptoms and diagnostic methods for this condition.

Article Abstract

Primary infection of the larynx with Aspergillus spp. is rare. It is more commonly seen as part of a wider infection involving the respiratory system in an immunocompromised host. In noncompromised patients laryngeal aspergillosis may represent colonization rather than invasion requiring no systemic anti-fungal treatment. The diagnosis is important as the presenting symptoms are suggestive of malignant laryngeal disease. We present a 62-year-old man with a short history of hoarseness. Direct laryngoscopy and biopsy confirmed the diagnosis of aspergillosis. Clinical presentation, diagnosis and the important pathological characteristics of this infection are discussed.

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http://dx.doi.org/10.1017/s0022215100128403DOI Listing

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