We describe a patient who, 4 years after a radical neck dissection and radiotherapy, presented with obstructive sleep apnea; upon bronchoscopy, he was found to have acquired laryngomalacia. Inspiration induced upper airway obstruction due to a large flaccid epiglottis, large aryepiglottic folds, and edema of the supraglottic area. We suggest that acquired laryngomalacia can lead to obstructive sleep apnea. Patients with obstructive sleep apnea after radical neck dissection need to be evaluated for laryngomalacia with fiberoptic laryngobronchoscopy. Examination of the upper airway is useful to determine the nature and extent of any upper airway collapse.
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http://dx.doi.org/10.1378/chest.106.6.1898 | DOI Listing |
Sleep
January 2025
Division of Pulmonary, Critical Care and Sleep Medicine, University at Buffalo, NY, USA.
Nat Sci Sleep
January 2025
Department of Stomatology, Gongli Hospital of Shanghai Pudong New Area, Shanghai, People's Republic of China.
Objective: Patients with obstructive sleep apnea (OSA) frequently suffer from migraine, however the causal relationship between OSA and migraine is unknown. Investigating the causation will assist in understanding the etiology of OSA and migraine.
Methods: Bidirectional two-sample Mendelian randomization (MR) and multivariable MR (MVMR) approaches were carried out to investigate the causal link between OSA and migraine.
Brain Behav Immun Health
December 2024
Department of Systems Medicine, University of Rome "Tor Vergata", 00133, Rome, Italy.
Background: Interleukin-6 (IL-6) represents one of the main molecules involved in inflammatory responses, which can be altered in either patients with cognitive impairment or obstructive sleep apnea (OSA). The present study aimed to evaluate serum IL-6 levels and cognitive performance in patients with severe OSA (Apnea-Hypopnea Index - AHI >30/h).
Methods: Thirty patients with severe OSA were compared to 15 controls similar in age, sex, and Body Mass Index.
Cleft Palate Craniofac J
January 2025
Sleep Medicine, Stanford University, Stanford, CA, USA.
It's interesting to note that despite clinical improvements in upper airway dimensions, the maxillary, mandibular, and mandibular body lengths remained smaller than those of controls. This finding may represent an underlying neurocristopathy, which represents a deficiency in the population of neural crest cells available in the embryonic maxillary and mandibular processes de novo. Indeed, it is known that craniofacial dimensions in infants with malformations, such as cleft palate, are often smaller when compared to non-cleft counterparts.
View Article and Find Full Text PDFChron Respir Dis
January 2025
Respiratory Research@Alfred, School of Translational Medicine, Monash University, Melbourne Australia.
Objectives: To assess the safety, reliability and acceptability of the modified incremental step test (MIST) supervised remotely via videoconferencing in adults with chronic respiratory disease.
Methods: Adults with chronic respiratory disease undertaking pulmonary rehabilitation were invited to undertake the MIST under two testing conditions: in-person supervision and remote supervision via video-conferencing. Test order was randomised.
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