Histological changes in chronic experimental hypocobaltosis manifest as atrophic-degenerative alterations and restructuring of endocrine organs as well as a decrease in systemic resistance (accidental transformation of the thymus, duodenitis and sigmoiditis in some animals). Pronounced fat hepatosis and signs of iron metabolism damage (cheilitis, spleen siderosis) are found as well.
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Histological changes in chronic experimental hypocobaltosis manifest as atrophic-degenerative alterations and restructuring of endocrine organs as well as a decrease in systemic resistance (accidental transformation of the thymus, duodenitis and sigmoiditis in some animals). Pronounced fat hepatosis and signs of iron metabolism damage (cheilitis, spleen siderosis) are found as well.
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