The technique of polymerase chain reaction was used to detect Pneumocystis carinii DNA in nasopharyngeal secretions of three infants with leukaemia who had the clinical features of P carinii pneumonia. The use of this non-invasive technique allowed the early diagnosis and treatment of these infants whose protocols did not include the use of prophylactic co-trimoxazole.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1029983PMC
http://dx.doi.org/10.1136/adc.71.3.254DOI Listing

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