Objective: This study is a multicenter, retrospective review of the initial clinical results of an artificial disc replacement, the LINK SB Charité intervertebral prosthesis.
Methods: Independent analysis by chart review included patient demographics, surgical data, and a comparison of presurgical to follow-up data. Data were analyzed from 93 patients (average age = 43.0 +/- 7.3) in whom a total of 139 Model III prostheses (Waldemar Link GmbH & Co, Hamburg, Germany) were implanted.
Results: The predominant diagnostic indication for the disc was degenerative disc disease (52.4%). The L4-L5 and L5-S1 levels comprised 87.1% of all levels implanted. The average follow-up was 11.5 +/- 8.4 months. After disc implantation, a significant proportion of the patient sample experienced pain relief (P < 0.05). Improvements were also noted in pain intensity, walking distance, lumbar mobility, and the percentage of patients showing a positive SLR or neurological weakness. No difference in work status after disc implantation could be detected. Device failure, migration, or dislocation occurred in 6 of 93 (6.5%) patients.
Conclusions: This study represents the largest multicenter case series of any functional artificial disc implantation. Carefully controlled, prospective studies that compare disc implantation and fusion are warranted.
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http://dx.doi.org/10.1097/00007632-199408150-00009 | DOI Listing |
J Oral Implantol
January 2025
Department of Neuroscience, Reproductive Sciences and Dentistry, Federico II University of Naples, Naples, Italy.
Purpose: This pilot study evaluated and compared histomorphometric and immunohistochemical characteristics of peri-implant bone tissue after implant site preparation using piezoelectric tips versus conventional drills.
Material And Methods: Six patients with bilateral partial edentulism underwent a splitmouth protocol. Twelve alveolar ridges were randomized into six control implant sites prepared using conventional drills (Drill Group); and six test implant sites prepared using piezoelectric implant inserts (Piezo Group).
Orthop Surg
January 2025
Department of Spinal Surgery, The Affiliated Hospital of Qingdao University, Qingdao, China.
Objectives: The advent of O-arm navigation optimized the oblique lumbar interbody fusion (OLIF) procedure, allowing the operator to simultaneously perform OLIF and percutaneous posterior pedicle screw implantation without patient position change, thus improving the fluency and accuracy of the OLIF procedure (called as OLIF360). Nevertheless, a consensus regarding its suitability for patients with severe spinal stenosis remains elusive. This study aims to investigate the clinical efficacy of OLIF360 and its imaging changes in severe lumbar spinal stenosis cases.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Materials Science and Engineering, Institute of Space Technology Islamabad Pakistan
Poor wear- and corrosion-resistance of 316L SS implants are critical problems in orthopedic implants. This study aims to improve the wear- and corrosion-resistance of 316L SS through surface coating. In this study, a bilayer composite coating consisting of polyether ether ketone (PEEK) as the first layer, and titania (TiO)- and Cu-doped mesoporous bioactive glass nanoparticles (Cu-MBGNs) were deposited as the second layer on a 316L SS electrophoretic deposition (EPD).
View Article and Find Full Text PDFSpine (Phila Pa 1976)
January 2025
Department of Orthopaedics, Xijing Hospital, Air Force Medical University, Xi'an China.
Study Design/setting: A retrospective cohort study.
Objective: To compare long-term outcomes and complications of cervical disc replacement (CDR) and anterior cervical discectomy and fusion (ACDF) with cage-plate constructs (CPC) and stand-alone (SA) cages in treating degenerative cervical spondylosis.
Summary Of Background Data: ACDF is commonly used for cervical radiculopathy but may increase adjacent segment degeneration (ASD).
Medicine (Baltimore)
January 2025
Ningbo Medical Center LiHuiLi Hospital, Ningbo, Zhejiang, PR China.
Rationale: Alkaptonuria (AKU) is a rare, inherited metabolic disease caused by deficient activity of homogentisic acid oxidase, leading to the accumulation of homogentisic acid and its oxidized product, benzoquinone acetic acid. These compounds cause black discoloration of cartilage, degeneration, inflammation, and calcification of intervertebral disks and large joints, resulting in pain and impaired quality of life. Despite its debilitating effects, there are no curative treatments for AKU, and management remains supportive.
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