[Measurements of DNA-ploidies in patients with carcinoma of the larynx].

Otolaryngol Pol

z Kliniki Otolaryngologii, Katedry Chorób Ucha, Nosa, Gardła i Krtani AM w Poznaniu.

Published: December 1994

In recent years there has been a lot of research done on using DNA-cytometry in the evaluation of larynx cancer. Everyone unanimously emphasizes that aneuploidal and polyploidal neoplasms require special therapeutical treatment. The definition of proliferating activity of neoplasm is of utmost importance. Other than diploidal amount of DNA is characteristic for cells fast dividing and incorrectly dividing. For the evaluation of own material, 20 cases of larynx cancer were collected and underwent a routine morphological and electron microscope evaluation, also flow-cytometry of DNA on Coulter apparatus was carried out. Generally, it can be said that cytometry of DNA in comparison with morphological examination has a secondary function but is nevertheless and important test. It allows the doctor to be more objective in evaluating the population of dividing cells.

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