The authors analyzed results of 295 labors induced with endocervical application of dinoprostin (152 term- and 143 postterm labors) in relation to 242 (125 term- and 117 postterm-) spontaneous labors. Delayed labor increases the occurrence of meconial amniotic fluid (21.96%:9.03% p < 0.01), and pathological and prepathological CTG records (23.85%: 11.97% p < 0.005). In addition, children show lower Apgar score (p < 0.001), and among them there are more hypertrophic (6.54%:2.53% p < 0.05), postterm (6.92%:0.0% p < 0.005), and dysmature children (11.92%:3.12% p < 0.01) when compared to children born between the days 274 and 287 of the gestational age. Perinatal morbidity of children born after 287 gestational days in rather high-32.31%. Induction of labor with endocervical application of prostine shortens the duration of the labor (p < 0.001). Large numbers of labors are finished with vacuum extraction-3.73% (3.29% of term- and 4.19% of postterm labors) and cesarear section-12.88% (10.53% of term- and 15.38% of postterm labors) usually due to dystocia of the uterus and hypoxion of the neonate. Labor trauma is the most usual trauma among perinatal problems of new born infants delivered by the induction with prostaglandins and high perinatal morbidity rate is due not only to the induction method but also to the incorrect assessment of the gestational age.
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PLoS Med
January 2025
Region Västra Götaland, Sahlgrenska University Hospital, Department of Obstetrics and Gynecology, Gothenburg, Sweden.
Background: The risk of perinatal death and severe neonatal morbidity increases gradually after 41 weeks of pregnancy. We evaluated maternal and perinatal outcomes after a national shift from expectancy and induction at 42+0 weeks to a more active management of late-term pregnancies in Sweden offering induction from 41+0 weeks or an individual plan aiming at birth or active labour no later than 42+0 weeks.
Methods And Findings: Women with a singleton pregnancy lasting 41+0 weeks or more with a fetus in cephalic presentation (N = 150,370) were included in a nationwide, register-based cohort study.
J Acquir Immune Defic Syndr
January 2025
Makerere University - Johns Hopkins University Research Collaboration, Kampala, Uganda.
Introduction: We assessed the risk of adverse pregnancy and birth outcomes and birth defects among women living with HIV (WLHIV) on antiretroviral therapy (ART) and HIV-negative women.
Methods: We analyzed data on live births, stillbirths, and spontaneous abortions during 2015-2021 from a hospital-based birth defects surveillance system in Kampala, Uganda. ART regimens were recorded from hospital records and maternal self-reports.
Med Acupunct
October 2024
College of Nursing, University of Utah, Salt Lake City, Utah, USA.
Purpose: Lay midwives attend most births at home in Guatemala facing many challenges with limited resources. Current research demonstrates that acupressure can reduce preterm contractions and encourage post-term labor. Sharing acupressure techniques with lay midwives could improve birth outcomes in Guatemala.
View Article and Find Full Text PDFEnviron Int
December 2024
Department of Epidemiology, Gillings School of Global Public Health, University of North Carolina at Chapel Hill, CB#7435, Chapel Hill, NC 27599-7435, United States. Electronic address:
Melamine, its analogues, and aromatic amines (AAs) were commonly detected in a previous study of pregnant women in the Environmental influences on Child Health Outcomes (ECHO) Cohort. While these chemicals have identified toxicities, little is known about their influences on fetal development. We measured these chemicals in gestational urine samples in 3 ECHO cohort sites to assess associations with birth outcomes (n = 1,231).
View Article and Find Full Text PDFEur J Obstet Gynecol Reprod Biol
December 2024
Department of Obstetrics and Gynecology, Hacettepe University Faculty of Medicine, Ankara, Turkey.
Purpose: To determine the reference values for the shock index (SI) in postpartum patients undergoing elective cesarean delivery with regional anesthesia.
Methods: This prospective study was conducted at our tertiary center between August 1, 2023, and March 1, 2024. We calculated the reference values for the SI within the first 48 h postpartum for patients who underwent elective cesarean delivery after the 34th week of gestation.
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