[Action of different cell types in influenza antibody production. 5. Keeping the immunologic memory to influenza virus A serotype by B- and T-lymphocytes].

The authors present data on the cooperation of the B- and T-lymphocytes in secondary immunological response to the antigens of influenza virus of serological type A. Cells of the spleen, bone marrow and the thymus in various combinations from the intact and immunized animals were transplanted to sublethally irradiated recipients; influenza virus was administered at the same time. Immunological memory to the virus antigens of serological type A proved to be preserved both by the B- and T-lymphocytes. Both in the primary and in the secondary response B-lymphocytes served as the precursors of cells-producers of antibodies.