Vesiculopustular diseases of neonates and infants can be divided into infectious and noninfectious categories. Recent clinical and scientific literature has focused mainly on the infectious diseases and on epidermolysis bullosa. This review covers the following disorders: neonatal sepsis, staphylococcal scaled skin syndrome, neonatal herpes simplex, neonatal varicella, congenital syphilis, scabies, mastocytosis, incontinentia pigmenti, eosinophilic pustular folliculitis, and epidermolysis bullosa.
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Detecting Monkeypox Virus by Immunohistochemistry.
J Cutan Pathol
December 2024
Department of Dermatology, University of Virginia, Charlottesville, Virginia, USA.
Background: Mpox (formerly known as monkeypox), a zoonotic disease caused by Monkeypox virus (MPXV), has become an international outbreak since May 2022. Mpox often presents with a mild systemic illness and a characteristic vesiculopustular skin eruption. In addition to molecular testing, histopathology of cutaneous lesions usually shows distinctive findings, such as epidermal necrosis, balloon degeneration, papillary dermal edema, and focal dermal necrosis, which have proven helpful in the diagnosis of mpox.
View Article and Find Full Text PDFComparative Analysis of 2022 Outbreak MPXV and Previous Clade II MPXV.
J Med Virol
November 2024
Department of Preventive Medicine, Public Health and Microbiology, Universidad Autónoma de Madrid, Madrid, Spain.
The 2022-2024 outbreak of MPOX is an important worldwide public health issue that has triggered significant concerns in the scientific community. MPOX is caused by monkeypox virus (MPXV) belonging to the Poxviridae family. The study of MPXV presents a multifaceted challenge due to the diverse viral formThis study was supported by ISIDORe consortium and Agencia Estatal de Investigación.
View Article and Find Full Text PDFA case of IgA pemphigus, with a poor response to dapsone, successfully treated with adalimumab.
Clin Case Rep
May 2024
Department of Dermatology, Razi Hospital Tehran University of Medical Sciences (TUMS) Tehran Iran.
Article Synopsis
- * The condition is characterized by itchy, blistering skin lesions, primarily affecting areas like the axilla and groin, due to IgA autoantibodies disrupting cell adhesion in the skin.
- * The study presents a case where a 50-year-old male with severe IgA pemphigus had a poor response to Dapsone but was successfully treated with an injection of the TNFa inhibitor, adalimumab.
Mpox across countries from Central and Eastern Europe - 2022 outbreak.
Travel Med Infect Dis
May 2024
Victor Babes Hospital for Infectious and Tropical Diseases, Bucharest, Romania; Carol Davila University of Medicine and Pharmacy, Bucharest, Romania. Electronic address:
Article Synopsis
- The study examined socio-demographic characteristics, clinical presentations, and outcomes of mpox patients across 14 Central and Eastern European countries.
- Nearly all of the 154 diagnosed patients were males, primarily men who have sex with men (MSM), with a significant proportion also living with HIV, who engaged in high-risk sexual behaviors.
- The findings suggest a need for effective contact tracing and vaccination strategies to manage mpox outbreaks, as the majority of cases presented favorable outcomes despite some complications.
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