Effect of Jian Yan Ling (JYL, mainly consisted of Succinum, Pteria margaritifers and Astragalus membranaceus etc.) on serum lipids was studied by double-blind method in 128 hyperlipemia patients. Patients were divided randomly into two groups, the test groups (64 cases) treated with JYL, while the other 64 cases treated with placebo as control for 3 months. Serum total cholesterol (TC), triglyceride (TG), TC-high density lipolipid-cholesterol (TC-HDL-C), apoproteins were observed before and after treatment. Results showed that the TC, TG, apoproteins and lipoprotein-a of test group were all dropped significantly after JYL treatment (P < 0.01). The results suggested that JYL could regulate the blood lipids and could also exert an effect of antiatherosclerosis through reducing blood lipoprotein-a level. It is worth while to use JYL as an antihyperlipemic agent clinically.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Influence of Kunth Flavonoids on Composition of Soil Microbial Community.
Int J Mol Sci
December 2024
Key Laboratory of Agro-Environment in Tropics, Ministry of Agriculture and Rural Affairs, Guangdong Engineering Research Centre for Modern Eco-Agriculture and Circular Agriculture, College of Natural Resources and Environment, South China Agricultural University, Guangzhou 510642, China.
, one of the world's most destructive invasive species, is known for causing significant ecological and economic harm. While extensive research has focused on its growth characteristics, secondary metabolites, and control measures, its chemical interactions with the environment-particularly the role of flavonoids in shaping soil microbial communities-remain underexplored. In this study, we identified and quantified ten flavonoids from root exudates using UPLC-MS, including Hispidulin, Isorhamnetin, and Mikanin.
View Article and Find Full Text PDFIntegration of the rat liver micronucleus assay into a 28-day treatment protocol: testing the genotoxicity of four small-molecule nitrosamines with different carcinogenic potencies and tumor target specificities.
Toxicol Sci
January 2025
National Center for Toxicological Research, U.S. Food and Drug Administration, Jefferson, AR, 72079, USA.
Several potent carcinogenic nitrosamines, including N-nitrosodiethylamine (NDEA) and N-nitrosodimethylamine (NDMA), induce micronuclei in the micronucleated hepatocyte (MNHEP) assay but not in the micronucleated reticulocyte (MNRET) assay. However, the MNHEP assay is not as frequently used as the MNRET assay for evaluating in vivo genotoxicity. The present study evaluated MN formation in the liver of Big Blue transgenic rats exposed to four small-molecule nitrosamines, NDMA, N-nitrosodiisopropylamine (NDIPA), N-nitrosoethylisoporpylamine (NEIPA), and N-nitrosomethylphenylamine (NMPA), using a repeat-dose protocol typically used for in vivo mutagenicity studies.
View Article and Find Full Text PDFTungsten oxide nanowire clusters anchored on porous carbon fibers as a sulfur redox mediator for lithium-sulfur batteries.
Nanoscale Adv
January 2025
School of Materials Science and Engineering, Hefei University of Technology Hefei 230009 China
Addressing the sluggish redox kinetics of sulfur electrodes and mitigating the shuttle effect of intermediate lithium polysulfides (LiPS) are crucial for the advancement of high-energy lithium-sulfur batteries. Here, we introduce a pioneering flexible self-supporting composite scaffold that incorporates tungsten oxide nanowire clusters anchored on core-shell porous carbon fibers (WO/PCF) for sulfur accommodation. The core of PCF serves as a robust electrode supporting scaffold, whereas the porous shell of PCF provides a 3D interconnected conductive network to accommodate sulfur, restrain polysulfide diffusion and buffer electrode expansion.
View Article and Find Full Text PDFConstructed the microflower-like NiFeO/CeO composites with high concentration of oxygen vacancies to accelerate the three-phase reaction in lithium-oxygen batteries.
J Colloid Interface Sci
February 2025
State Key Lab of Physical Chemistry of Solid Surface, Fujian Key Laboratory of Surface and Interface Engineering for High Performance Materials, College of Materials, Xiamen University, Xiamen 361005, China. Electronic address:
Article Synopsis
- - The study focuses on creating efficient catalysts, specifically NiFeO/CeO composites, to improve lithium-oxygen battery performance by enhancing the three-phase reaction at the cathode side.
- - These composites feature a micro-flower structure that increases accessibility to active sites and combines the benefits of NiFeO's oxygen evolution and CeO's oxygen reduction activities.
- - The developed catalyst achieves impressive results, including 343 stable cycles, a round-trip efficiency of 97.8%, and a discharge capacity of 7478 mAh/g, showcasing potential for fast charging and long-lasting performance.
Targeting PDGF-CC as a promising therapeutic strategy to inhibit cholangiocarcinoma progression.
J Transl Med
November 2024
Department of Hepatobiliary surgery, the Third Affiliated Hospital of Southern Medical University, 183 Zhongshan Avenue West, Tianhe District, Guangzhou, 510630, Guangdong, China.
Article Synopsis
- Cholangiocarcinoma (CCA) is a severe cancer with few treatment options, and the study focuses on the role of Platelet-Derived Growth Factor CC (PDGF-CC) in its progression.
- Researchers compared PDGF-CC levels in CCA and normal tissues and found elevated mRNA and protein levels in CCA, linking high PDGF-CC expression to worse survival rates for patients.
- By depleting PDGF-CC in various cell lines and using xenograft models, the study demonstrated that reducing PDGF-CC leads to decreased cancer cell growth and suggests that targeting PDGF-CC could be a promising therapeutic approach for CCA.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!