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Resveratrol-Loaded Versatile Nanovesicle for Alopecia Therapy via Comprehensive Strategies.
Int J Nanomedicine
December 2024
School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou, Guangdong Province, People's Republic of China.
Introduction: Alopecia is a systemic disease with multiple contributing factors. Effective treatment is challenging when only hair growth mechanisms are targeted while ignoring the role of maintaining hair follicle microenvironment homeostasis, which is crucial for cell growth and angiogenesis. Oxidative stress and inflammation are major disruptors of this microenvironment, leading to inhibited cell proliferation and compromised hair follicle circulation.
View Article and Find Full Text PDFDiffuse face and ear hypertrichosis caused by 5% topical minoxidil in an adult woman with spontaneous resolution.
Dermatol Online J
August 2024
Dermatology and Dermatologic Surgery Department, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Minoxidil is a vasodilator medication known for its ability to promote hair growth. Although it was first introduced as an oral drug to treat hypertension, minoxidil was observed to have the important side-effect of increasing hair growth. This led to the development of a topical formulation as a 2% concentration solution for the treatment of female androgenic alopecia (AGA) and 5% for treating male AGA, which is considered as a first line U.
View Article and Find Full Text PDFArticle Synopsis
- * The review analyzed 286 articles, ultimately including 11 studies with over 19,000 patients; it found injectable minoxidil significantly improved hair growth for androgenetic alopecia, while results for alopecia areata varied.
- * Overall, injectable minoxidil appears to be a safe and effective treatment for androgenetic alopecia, with further research needed to determine optimal dosing and understand its effects on alopecia areata.
Australian dermatologists' prescribing behaviours for female androgenetic alopecia.
Australas J Dermatol
December 2024
Sinclair Dermatology, Melbourne, Victoria, Australia.
Female androgenetic alopecia (FAGA) affects approximately half of women during their lifetime and can have significant psychological impact. Despite its prevalence, treatment options have traditionally been limited. In this study, we examined the current prescribing patterns of Australian dermatologists for FAGA (n = 54), including the use of spironolactone, systemic minoxidil, topical minoxidil and combination treatments.
View Article and Find Full Text PDFDermal Filler-Induced Alopecia: A Case Report and Literature Review.
J Cosmet Dermatol
November 2024
Department of Dermatology, King Fahad Medical City, Riyadh, Saudi Arabia.
Background: Dermal filler-induced alopecia is a rare yet significant complication of aesthetic procedures primarily associated with vascular occlusion and subsequent tissue ischemia. Hyaluronic acid (HA) fillers, though widely used for facial rejuvenation, can lead to adverse outcomes such as skin necrosis and hair loss, particularly in high-risk areas like the temples and glabella.
Objective: This case report aims to highlight the clinical presentation, diagnostic approach, and multidisciplinary management of filler-induced alopecia, contributing to the existing literature with a comprehensive review of previously reported cases.
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