Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
AshPhos Ligand: Facilitating Challenging Aminations in Five- and Six-Membered Heteroaryl Halides Using Cyclic Secondary and Bulky Amines.
JACS Au
January 2025
Department of Chemistry, University of Missouri, 601 South College Avenue, Columbia, Missouri 65211, United States.
Our newly developed AshPhos ligand represents a significant advancement in Buchwald-Hartwig aminations, overcoming many limitations of existing ligands. Created from affordable and accessible materials, AshPhos enhances catalytic performance, especially for extremely difficult substrates, by emphasizing the principles of ligand chelation and cooperativity. Its successful synthesis and application in catalytic aminations underscore its potential for use in the sustainable synthesis of compounds important to medicinal chemistry, materials, and energy.
View Article and Find Full Text PDFCitrate: a key signalling molecule and therapeutic target for bone remodeling disorder.
Front Endocrinol (Lausanne)
January 2025
Department of Orthopedics, The First Hospital of China Medical University, Shenyang, China.
Bone remodeling is a continuous cyclic process that maintains and regulates bone structure and strength. The disturbance of bone remodeling leads to a series of bone metabolic diseases. Recent studies have shown that citrate, an intermediate metabolite of the tricarboxylic acid (TCA) cycle, plays an important role in bone remodeling.
View Article and Find Full Text PDFGreen light-responsive photoelectrochemical sensing nanoplatform based on copper cobaltite nanorods for ultrasensitive detection of furazolidone antibiotic residue in food samples.
RSC Adv
January 2025
Phenikaa University Nano Institute (PHENA), PHENIKAA University Hanoi 12116 Vietnam
In this research, the preparation of copper cobaltite (CuCoO) nanorods and its potential application in photoelectrochemical sensing platform towards ultrasensitive detection of furazolidone are reported. X-ray diffraction, Raman spectra, scanning electron microscopy, and UV-visible spectroscopy have been performed to confirm the formation, morphology, phase composition, and optical properties of CuCoO synthesized by a microwave-assisted hydrothermal method. The electrochemical characteristic parameters were calculated electrochemical impedance spectroscopy, cyclic voltammetry, differential pulse voltammetry, and chronoamperometry techniques in the absence and presence of laser light irradiation.
View Article and Find Full Text PDFDetection of chronic wasting disease prions in the farm soil of the Republic of Korea.
mSphere
January 2025
WOAH Reference Laboratory for CWD, Foreign Animal Disease Division, Animal and Plant Quarantine Agency, Gimcheon, South Korea.
Chronic wasting disease (CWD) is a highly contagious prion disease occurring in free-ranging and farmed cervids. CWD continues to spread uncontrolled across North America, and cases continue to be detected almost every year in the Republic of Korea. CWD-infected animals contaminate the soil by releasing infectious prions through their excreta, and shed prions accumulate and remain infectious in the soil for years.
View Article and Find Full Text PDFElectrochemical Denitrative Cyclization Driven by Alternating Polarity.
Org Lett
January 2025
Key Laboratory of Molecule Synthesis and Function Discovery (Fujian Province University), College of Chemistry, Fuzhou University, Fuzhou 350108, China.
Alternating current electrolysis has emerged as a promising technique for addressing challenging redox reactions that are otherwise difficult or impossible for direct current electrolysis. Under mild and transition-metal-free reaction conditions, a general electrochemical denitrative cyclization of nitroarenes was developed to access various cyclic sulfone-containing derivatives of biological significance. The key to success lies in the facile manipulation of multiple redox events upon rapid alternating polarity switching to enhance the selectivity and efficiency.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!