The relative dose distribution around the 103Pd model 200 implant seed was measured with a computerized data acquisition system employing a p-n junction silicon diode immersed in a water phantom. Data are acquired in polar coordinates by computer control of (1) the diode distance from the seed center and (2) the rotation angle of seed about a transverse axis. Transverse axis data are compared with thermoluminescent dosimeter (TLD) measurements and a Monte Carlo calculation by others.
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http://dx.doi.org/10.1118/1.597327 | DOI Listing |
Brachytherapy
January 2025
Department of Genitourinary Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX.
Background: To determine outcomes of MRI-assisted radiosurgery (MARS) for salvage brachytherapy using the radioisotope Pd after various upfront treatments including surgery, external beam radiotherapy, and brachytherapy.
Methods: We retrospectively reviewed data for patients who underwent salvage MARS for intraprostatic lesions or prostate bed recurrences from 2016 to 2022. Biochemical recurrence, prostate cancer-specific, and overall survival, and the cumulative incidences of toxicities, were determined by Kaplan-Meier estimates.
EJNMMI Radiopharm Chem
May 2024
Department of Pharmaceutical Sciences, University of Toronto, Toronto, ON, Canada.
Background: Radiation nanomedicines are nanoparticles labeled with radionuclides that emit α- or β-particles or Auger electrons for cancer treatment. We describe here our 15 years scientific journey studying locally-administered radiation nanomedicines for cancer treatment. We further present a view of the radiation nanomedicine landscape by reviewing research reported by other groups.
View Article and Find Full Text PDFAppl Radiat Isot
April 2022
Department of Physics, Faculty of Science, University of Guilan, Rasht, Iran.
Knowledge of the energy deposition in different eye components is a critical decision-making to the overall effectivity of ocular melanoma treatment with plaques loaded with low-energy sources. The aim of this study is using the GATE 8.2 Monte Carlo code to calculate the 3D dose distribution in a realistic eye model.
View Article and Find Full Text PDFCureus
June 2021
Radiation Oncology, Duke University, Durham, USA.
Brachytherapy
October 2021
Carleton Laboratory for Radiotherapy Physics, Department of Physics, Carleton University, Ottawa, Canada. Electronic address:
Purpose: Permanent breast seed implant using Pd is emerging as an effective adjuvant radiation technique for early stage breast cancer. However, clinical dose evaluations follow the water-based TG-43 approach with its considerable approximations. Toward clinical adoption of advanced TG-186 model-based dose evaluations, this study presents a comprehensive investigation for permanent breast seed implant considering both target and normal tissue doses.
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