During 1990, Dengue-2 (DEN-2) virus was isolated for the first time from mosquitoes (Aedes furcifer, six isolates; Ae. taylori, six isolates; Ae. luteocephalus, seven isolates) collected during an epidemic in which DEN-2 virus also was isolated from humans. Numerous isolations have been made previously from mosquitoes in the absence of human infection. In Senegal, DEN-2 virus appears to be maintained in an enzootic cycle and, therefore, plays an expanding role in human disease and increases the need for effective surveillance in mosquito populations.
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